Evidence map›Paper›PMID 28402073›Full record

ReviewBirth defects research2017

Infantile Hemangiomas: An Updated Review on Risk Factors, Pathogenesis, and Treatment.

Chelsey J Forbess Smith, Sheila Fallon Friedlander, Monica Guma, Arthur Kavanaugh, Christina D Chambers

Abstract readReview
In one paragraph

Review in Birth defects research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 131 citations in OpenAlex.

  1. Risk factors for infantile hemangioma: a meta-analysis.World journal of pediatrics : WJP · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Hypoxia-driven angiogenesis and metabolic reprogramming in vascular tumors.Frontiers in cell and developmental biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Pediatric Vascular Anomalies: A Clinical and Radiological Perspective.The Indian journal of radiology & imaging · 2024
    Review
  16. Review
  17. Review
  18. Review
  19. Infantile hemangioma models: is the needle in a haystack?Journal of translational medicine · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chelsey J Forbess SmithDepartment of Rheumatology, University of California San Diego, San Diego, California.
Sheila Fallon FriedlanderDepartment of Pediatric and Adolescent Dermatology, University of California San Diego, San Diego, California.
Monica GumaDepartment of Rheumatology, University of California San Diego, San Diego, California.
Arthur KavanaughDepartment of Rheumatology, University of California San Diego, San Diego, California.
Christina D ChambersDepartment of Pediatrics, University of California San Diego, San Diego, California.
University of San Diego · USUniversity of California, San Diego · US

Funding

Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
NIAMS NIH HHS T32 AR064194
6 · The paper itself

Abstract

Infantile hemangiomas (IHs) are the most common vascular tumors in infants, appearing in early infancy and ultimately regressing with time. Clinical presentation may vary, with a minority of lesions causing impairment of vital function (e.g., respiratory or visual obstruction), permanent scarring, and/or disfigurement. The pathogenesis of IH is complex and poorly understood. Risk factors implicated in their development include preterm birth and placental anomalies. IH presents a myriad of clinical challenges, including correct diagnosis and whether or not to pursue treatment. This article is a review of the current literature regarding pathogenesis, clinical presentation, treatment, and prognosis of IH. Birth Defects Research 109:809-815, 2017. © 2017 Wiley Periodicals, Inc.

Indexed as

FemaleHemangiomaHemangioma, CapillaryHumansInfantInfant, NewbornMalePlacenta DiseasesPregnancyPrognosisRisk FactorsTreatment OutcomeVascular Neoplasmsbeta blockadeglucose transporter-1 (GLUT-1)hemangiomahypoxiapregnancyvascular endothelial growth factor (VEGF)

Identifiers

PMID28402073
PMCPMC5839165
OpenAlexW2607136239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.