ReviewNature reviews. Urology2017
Incontinence in the elderly, 'normal' ageing, or unaddressed pathology?
Review in Nature reviews. Urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Randomized trial of transcutaneous tibial nerve stimulation to treat overactive bladder in older women.PloS one · 2026Trial
- Keratin 20 deficiency phenocopies human UAB and drives bladder fibrosis via a mechanotransduction-TGF-β axis.iScience · 2026Article
- Are pelvic floor muscle function, quadriceps femoris muscle, gluteus medius muscle, hand grip strength and functional performance affected by incontinence types in elderly people with urinary incontinence?International urology and nephrology · 2025Article
- Hypoxanthine Induces Signs of Bladder Aging With Voiding Dysfunction and Lower Urinary Tract Remodeling.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Quantification of Aging-Related Decreases in Sensory Innervation of the Bladder Trigone in Rats.International neurourology journal · 2024Article
- The brain, gut, and bladder health nexus: A conceptual model linking stress and mental health disorders to overactive bladder in women.Neurourology and urodynamics · 2024Article
- A 10- to 20-year follow-up after tension-free vaginal tape for stress urinary incontinence.International urogynecology journal · 2023Article
- Purine nucleoside phosphorylase as a target to treat age-associated lower urinary tract dysfunction.Nature reviews. Urology · 2022Review
- Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium.International neurourology journal · 2022Article
- A uro-protective agent with restorative actions on urethral and striated muscle morphology.World journal of urology · 2021Article
- Efficacy and Safety of Mirabegron in Men with Overactive Bladder Symptoms and Benign Prostatic Hyperplasia.Current urology reports · 2021Review
- Urinary urgency acts as a source of divided attention leading to changes in gait in older adults with overactive bladder.PloS one · 2021Article
- Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions.JCI insight · 2020Article
- Continence: Bowel and Bladder and Physical Function Decline in Women.Current geriatrics reports · 2020Article
- Mirabegron in the Treatment of Overactive Bladder: Safety and Efficacy in the Very Elderly Patient.Clinical interventions in aging · 2020Review
- Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction-A Novel Hypothesis.Frontiers in surgery · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of urinary incontinence and other lower urinary tract symptoms (LUTS) increases in association with increasing age. This effect is more noticeable in men after the seventh decade of life and, in women, postmenopausally. However, the changes in the lower urinary tract, peripheral nervous system and central nervous system that underpin this observation are both multifactorial and inadequately understood; much debate exists regarding whether these observed changes are pathological or are a part of the 'normal' ageing process; with both health professionals and older people often holding the view that incontinence is an expected part of normal ageing. Here we aim to summarize the current level of knowledge regarding the physiological and hormonal changes that take place during the ageing process and discuss whether the occurrence of urinary incontinence or other LUTS in later life better reflect part of the 'normal' ageing process or the presence of unaddressed pathology.
Indexed as
Identifiers
28401955What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.