ArticleDevelopment and psychopathology2017
Poverty, early care, and stress reactivity in adolescence: Findings from a prospective, longitudinal study in South Africa.
Article in Development and psychopathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- Empirical Evidence for the Developmental Origins of Autonomic Stress Regulation: An Attachment Account.Developmental psychobiology · 2026Article
- Longitudinal associations between violence exposure and adolescent conduct problems in a high-adversity, South African setting.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Preschool care early in life and mental health in adolescence in Sweden: a cohort study.BMJ open · 2026Article
- The role of pubertal development in the association between trauma and internalising symptoms in female youth.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Childhood adversity and peer influence in adolescent bullying perpetration.Scientific reports · 2024Article
- The Development of Stress Reactivity and Regulation in Children and Adolescents.Current neuropharmacology · 2024Review
- A perspective-based analysis of attachment from prenatal period to second year postnatal life.Frontiers in psychology · 2024Review
- Does Adulthood Socioeconomic Status Predict Subsequent Telomere Length in Racially and Ethnically Diverse Women?Journal of biomedical and life sciences · 2024Article
- Childhood adversity during the post-apartheid transition and COVID-19 stress independently predict adult PTSD risk in urban South Africa: A biocultural analysis of the stress sensitization hypothesis.American journal of biological anthropology · 2023Article
- Evaluating the mental health impacts of the COVID-19 pandemic: perceived risk of COVID-19 infection and childhood trauma predict adult depressive symptoms in urban South Africa.Psychological medicine · 2022Article
- Comorbid depression and anxiety: Integration of insights from attachment theory and cognitive neuroscience, and their implications for research and treatment.Frontiers in behavioral neuroscience · 2022Article
- Maternal Shared Pleasure, Infant Withdrawal, and Developmental Outcomes in a High Risk Setting in South Africa.Frontiers in psychiatry · 2021Article
- What is resilience: an affiliative neuroscience approach.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
- Mothering from the Inside Out: Adapting an evidence-based intervention for high-risk mothers in the Western Cape of South Africa.Development and psychopathology · 2020Article
- Emerging Opportunities Provided by Technology to Advance Research in Child Health Globally.Global pediatric health · 2020Article
- Dimensionality of Early Adversity and Associated Behavioral and Emotional Symptoms: Data from a Sample of Japanese Institutionalized Children and Adolescents.Child psychiatry and human development · 2019Article
- Adrenocortical Responses to Daily Stressors Are Calibrated by Early Life Adversity: An Investigation of the Adaptive Calibration Model.Evolutionary psychology : an international journal of evolutionary approaches to psychology and behaviorArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
Abstract
A considerable body of evidence suggests that early caregiving may affect the short-term functioning and longer term development of the hypothalamic-pituitary-adrenocortical axis. Despite this, most research to date has been cross-sectional in nature or restricted to relatively short-term longitudinal follow-ups. More important, there is a paucity of research on the role of caregiving in low- and middle-income countries, where the protective effects of high-quality care in buffering the child's developing stress regulation systems may be crucial. In this paper, we report findings from a longitudinal study (N = 232) conducted in an impoverished periurban settlement in Cape Town, South Africa. We measured caregiving sensitivity and security of attachment in infancy and followed children up at age 13 years, when we conducted assessments of hypothalamus-pituitary-adrenocortical axis reactivity, as indexed by salivary cortisol during the Trier Social Stress Test. The findings indicated that insecure attachment was predictive of reduced cortisol responses to social stress, particularly in boys, and that attachment status moderated the impact of contextual adversity on stress responses: secure children in highly adverse circumstances did not show the blunted cortisol response shown by their insecure counterparts. Some evidence was found that sensitivity of care in infancy was also associated with cortisol reactivity, but in this case, insensitivity was associated with heightened cortisol reactivity, and only for girls. The discussion focuses on the potentially important role of caregiving in the long-term calibration of the stress system and the need to better understand the social and biological mechanisms shaping the stress response across development in low- and middle-income countries.
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Registered trials
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