Evidence map›Paper›PMID 28401489›Full record

ArticleNeuroscience bulletin2018

Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice.

Peng-Bo Jing, De-Li Cao, Si-Si Li, Meixuan Zhu, Xue-Qiang Bai, Xiao-Bo Wu, Yong-Jing Gao

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  3. Benefits ofInternational journal of molecular sciences · 2025
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  18. Article
  19. Physiology and Pathophysiology of Itch.Physiological reviews · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peng-Bo JingPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
De-Li CaoPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
Si-Si LiPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
Meixuan ZhuPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
Xue-Qiang BaiPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
Xiao-Bo WuPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
Yong-Jing GaoPain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China. gaoyongjing@ntu.edu.cn.
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that the chemokine receptor CXCR3 and its ligand CXCL10 in the dorsal root ganglion mediate itch in experimental allergic contact dermatitis (ACD). CXCR3 in the spinal cord also contributes to the maintenance of neuropathic pain. However, whether spinal CXCR3 is involved in acute or chronic itch remains unclear. Here, we report that Cxcr3

Indexed as

AcetamidesAnimalsChemokine CXCL10ChloroquineChronic DiseaseCyclopropanesDehydrationDinitrofluorobenzeneDisease Models, AnimalFormaldehydeFreund's AdjuvantMiceMice, Inbred C57BLMice, KnockoutMotor ActivityPainAcetamidesChemokine CXCL10ChloroquineCxcl10 protein, mouseCxcr3 protein, mouseCyclopropanesDinitrofluorobenzenediphenylcyclopropenoneFormaldehydeFreund's AdjuvantNBI-74330p-Methoxy-N-methylphenethylaminePyrimidinesReceptors, CXCR3AlloknesisChronic itchCXCL10CXCR3Dry skinSpinal cord

Identifiers

PMID28401489
PMCPMC5799116
OpenAlexW2605448993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.