ArticleFolia microbiologica2017
Analysis of antimicrobial and immunomodulatory substances produced by heterofermentative Lactobacillus reuteri.
Article in Folia microbiologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
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- The Role of ProbioticsInternational journal of molecular sciences · 2026Review
- Gut Microbiota and Dopamine: Producers, Consumers, Enzymatic Mechanisms, and In Vivo Insights.Bioengineering (Basel, Switzerland) · 2025Review
- Metabolic Characterization of Two Flor Yeasts During Second Fermentation in the Bottle for Sparkling Wine Production.International journal of molecular sciences · 2025Article
- Grape Pomace Fibres as a Sustainable Fining Agent to Ensure Red Wine Safety: A First Approach in a Continuous System.Foods (Basel, Switzerland) · 2025Article
- [Low-intensity pulsed ultrasound combined with nystatin treatment synergistically inhibits vaginalNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- BTS1-knockoutFrontiers in cellular and infection microbiology · 2025Article
- Genomic and phenotypic characterization of two novel human-derivedFrontiers in microbiology · 2025Article
- The Impact ofMicroorganisms · 2024Review
- A catalog of ethanol-producing microbes in humans.Future microbiology · 2024Review
- Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4Journal of nanobiotechnology · 2023Article
- Efficacy and mechanism ofFrontiers in cellular and infection microbiology · 2023Article
- Anti-Amnesic Effect of Synbiotic Supplementation ContainingInternational journal of molecular sciences · 2022Article
- Development of probiotics beverage using cereal enzymatic hydrolysate fermented withFood science & nutrition · 2022Article
- Polyphenols andJournal of preventive medicine and hygiene · 2022Review
- Untargeted Metabolomics Sensitively Differentiates Gut Bacterial Species in Single Culture and Co-Culture Systems.ACS omega · 2022Article
- Review
- Heat-killedFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Antimicrobial and immunomodulatory potential of various Lactobacillus reuteri strains is closely connected to their metabolite production profile under given cultivation conditions. We determined the in vitro production of antimicrobial substances such as organic acids, ethanol, and reuterin by four strains of L. reuteri (L. reuteri E, L. reuteri KO5, L. reuteri CCM 3625, and L. reuteri ATCC 55730). All studied L. reuteri strains showed the ability to produce lactic acid, acetic acid, and ethanol with concominant consumption of glucose and together with phenyllactic acid-a potent antifungal compound-with concominant consumption of phenylalanine. The reuterin production from glycerol was confirmed for all analyzed lactobacilli strains except L. reuteri CCM 3625. Production of organic acids, ethanol, and reuterin is significantly involved in antimicrobial activity of lactobacilli which was determined using the dual-culture overlay diffusion method against six indicator bacteria and five indicator moulds. In comparison to the referential L. reuteri ATCC 55730, the highest inhibition potential was observed against Escherichia coli CCM 3988 and Pseudomonas aeruginosa CCM 3955. Among analyzed indicators of moulds, the growth of Alternaria alternata CCM F-128 was the most inhibited by all four analyzed L. reuteri strains. Finally, the immunomodulatory potential of analyzed lactobacilli were proven by the determination of the in vitro production of biogenic amines histamine and tyramine. L. reuteri CCM 3625 was able to produce tyramine, and L. reuteri E and L. reuteri KO5 were able to produce histamine under given cultivation conditions.
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Registered trials
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