Evidence map›Paper›PMID 28401351›Full record

ArticleMedical microbiology and immunology2017

Quantification of intrahepatic total HBV DNA in liver biopsies of HBV-infected patients by a modified version of COBAS

Romina Salpini, Lorenzo Piermatteo, Upkar Gill, Arianna Battisti, Francesca Stazi, Tania Guenci, Sara Giannella, Valentina Serafini, Patrick T F Kennedy, Carlo Federico Perno and 2 more

Abstract readEvaluation Study
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In one paragraph

Article in Medical microbiology and immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Romina SalpiniDepartment of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Lorenzo PiermatteoDepartment of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Upkar GillHepatology, Centre for Immunobiology, Blizard Institute, Barts and The London SMD, QMUL, London, UK.
Arianna BattistiDepartment of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Francesca StaziLaboratory of Molecular Virology, Polyclinic Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy.
Tania GuenciLaboratory of Molecular Virology, Polyclinic Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy.
Sara GiannellaLaboratory of Molecular Virology, Polyclinic Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy.
Valentina SerafiniLaboratory of Molecular Virology, Polyclinic Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy.
Patrick T F KennedyHepatology, Centre for Immunobiology, Blizard Institute, Barts and The London SMD, QMUL, London, UK.
Carlo Federico PernoDepartment of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Valentina SvicherDepartment of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Marco CiottiLaboratory of Molecular Virology, Polyclinic Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy. marco.ciotti@ptvonline.it.
Policlinico Tor Vergata · ITUniversity of Rome Tor Vergata · ITQueen Mary University of London · GB

Funding

Department of Health PB-PG-0614-34087
6 · The paper itself

Abstract

Intrahepatic total HBV DNA (it-HBV DNA) level might reflect the size of virus reservoir and correlate with the histological status of the liver. To quantitate it-HBV DNA in a series of 70 liver biopsies obtained from hepatitis B chronic patients, a modified version of the COBAS

Indexed as

AdultBiopsyDNA, ViralFemaleHepatitis B, ChronicHepatitis B virusHumansLiverMaleReproducibility of ResultsViral LoadDNA, ViralCOBAS® TaqMan HBV test, v2.0HBV DNA levelHBV reservoirIntrahepatic HBV DNA

Identifiers

PMID28401351
OpenAlexW2605764970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.