Evidence map›Paper›PMID 28401130›Full record

ArticleCMAJ open

Development of a preliminary essential medicines list for Canada.

Michael S Taglione, Haroon Ahmad, Morgan Slater, Babak Aliarzadeh, Richard H Glazier, Andreas Laupacis, Nav Persaud

Open access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Access and use of WHO essential medicines in Italy.Frontiers in public health · 2023
    Article
  5. Article
  6. Article
  7. Pharmacare in Canada: The paediatric perspective.Paediatrics & child health · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. List of essential medicines for Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
  13. Estimated effects of adding universal public coverage of an essential medicines list to existing public drug plans in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Michael S TaglioneFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Haroon AhmadFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Morgan SlaterFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Babak AliarzadehFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Richard H GlazierFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Andreas LaupacisFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
Nav PersaudFaculty of Medicine (Taglione), University of Toronto; Li Ka Shing Knowledge Institute (Taglione, Ahmad, Glazier, Laupacis, Persaud); Department of Family and Community Medicine (Slater, Glazier, Persaud), St. Michael's Hospital; Department of Family and Community Medicine (Aliarzadeh, Glazier, Laupacis, Persaud), University of Toronto; University of Toronto Practice Based Research Network (Aliarzadeh); Institute for Clinical Evaluative Sciences (Glazier), Toronto, Ont.
St Michaels Hospital · GBLi Ka Shing Foundation · CNResearch Network (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome evidence supports the use of a short list of essential medicines to improve prescribing. We aimed to create a preliminary essential medicines list for use in Canada.

methodsThe 2013 World Health Organization Model List of Essential Medicines was initially adapted by the research team. Fourteen Canadian clinicians gave suggestions for changes to the list. Literature relevant to each unique suggestion was gathered and presented to 3 clinician-scientists who used a modified nominal group technique to make recommendations on the suggested changes. Audits of prescriptions of 2 Toronto-based family health teams (an inner city clinic and a suburban site) between Aug. 1, 2013, and July 30, 2014, were performed to identify common prescriptions that were not on the draft list. Literature relevant to these additional medications was gathered and shared with the clinician-scientist review panel to determine whether each should be added to the list, and a list was developed. The audits were repeated based on the final list to provide a preliminary assessment of the coverage of the list.

resultsThe multistep process produced a list of 125 medications. The medications included on this list covered 90.8% and 92.6% of prescriptions at the inner city clinic and the suburban site, respectively. In total, 93% of the patients seen at the inner city clinic and 96% of the patients seen at the suburban clinic had all or all but 1 of their medications covered by the list.

interpretationA preliminary list of essential medicines was developed that covered most, but not all, prescriptions at 2 primary care sites. The list should be further refined based on wider input.

Identifiers

PMID28401130
PMCPMC5378503
OpenAlexW2592468605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.