ArticleCMAJ open
Long-term sedative use among community-dwelling adults: a population-based analysis.
Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Deprescribing Benzodiazepine Receptor Agonists in Older Adults and People With Cognitive Impairment: A Systematic Review.Journal of the American Geriatrics Society · 2025Pooled it
- Brief interventions targeting long-term benzodiazepine and Z-drug use in primary care: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2020Pooled it
- Trial
- Multimorbidity patterns as predictors of sleeping medication use: a population-based study in women in Southern Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Article
- Trends and patterns of benzodiazepines and Z-drugs prescriptions in Australian general practice: A national study (2011-2018).Drug and alcohol review · 2023Article
- Addressing Barriers to Reducing Prescribing and Implementing Deprescribing of Sedative-Hypnotics in Primary Care.The Annals of pharmacotherapy · 2022Article
- Long-term benzodiazepines and z-drug prescribing in Australian general practice between 2011 and 2018: A national study.Pharmacology research & perspectives · 2022Article
- Physician Financial Incentives to Reduce Unplanned Hospital Readmissions: an Interrupted Time Series Analysis.Journal of general internal medicine · 2021Observational
- The patterns and burden of multimorbidity in geriatric patients with prolonged use of addictive medications.Aging clinical and experimental research · 2021Article
- One-year persistence of potentially inappropriate medication use in older adults: A population-based study.British journal of clinical pharmacology · 2020Article
- Use of benzodiazepines and z-drugs not compliant with guidelines and associated factors: a population-based study.European archives of psychiatry and clinical neuroscience · 2020Article
- Changes in Australian Early-Career General Practitioners' Benzodiazepine Prescribing: a Longitudinal Analysis.Journal of general internal medicine · 2018Article
- Benzodiazepine and Z-drug prescribing in Ireland: analysis of national prescribing trends from 2005 to 2015.British journal of clinical pharmacology · 2018Article
- Patterns, predictors and persistence of chronic sedative use: a population-based observational study of older adults in British Columbia, Canada.European journal of clinical pharmacology · 2017Observational
- Point Prevalence Survey of Benzodiazepine and Sedative-Hypnotic Drug Use in Hospitalized Adult Patients.The Canadian journal of hospital pharmacyArticle
- Prevalence of and pathways to benzodiazepine use in Brazil: the role of depression, sleep, and sedentary lifestyle.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic use of benzodiazepines and benzodiazepine-like sedatives (z-drugs) presents substantial risks to people of all ages. We sought to assess trends in long-term sedative use among community-dwelling adults in British Columbia.
methodsUsing population-based linked administrative databases, we examined longitudinal trends in age-standardized rates of sedative use among different age groups of community-dwelling adults (age ≥ 18 yr), from 2004 to 2013. For each calendar year, we classified adults as nonusers, short-term users, or long-term users of sedatives based on their patterns of sedative dispensation. For calendar year 2013, we applied cross-sectional analysis and estimated logistic regression models to identify health and socioeconomic risk factors associated with long-term sedative use.
resultsMore than half (53.4%) of long-term users of sedatives in British Columbia are between ages 18 and 64 years (young and middle-aged adults). From 2004 to 2013, long-term sedative use remained stable among adults more than 65 years of age (older adults) and increased slightly among young and middle-aged adults. Although the use of benzodiazepines decreased during the study period, the trend was offset by equal or greater increases in long-term use of z-drugs. Being an older adult, sick, poor and single were associated with increased odds of long-term sedative use.
interpretationDespite efforts to stem such patterns of medication use, long-term use of sedatives increased in British Columbia between 2004 and 2013. This increase was driven largely by increased use among middle-aged adults. Future deprescribing efforts that target adults of all ages may help curb this trend.
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Registered trials
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