Evidence map›Paper›PMID 28400808›Full record

ArticleNeural regeneration research2017

DCDC2 gene polymorphisms are associated with developmental dyslexia in Chinese Uyghur children.

Yun Chen, Hua Zhao, Yi-Xin Zhang, Peng-Xiang Zuo

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Study of Genetic Association WithClinical practice and epidemiology in mental health : CP & EMH · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yun ChenMedical College, Shihezi University, Shihezi, Xinjiang Uyghur Autonomous Region, China.
Hua ZhaoMedical College, Shihezi University, Shihezi, Xinjiang Uyghur Autonomous Region, China.
Yi-Xin ZhangSpecial Clinic Department, the 12 Hospital of People's Liberation Army, Kashgar, Xinjiang Uyghur Autonomous Region, China.
Peng-Xiang ZuoMedical College, Shihezi University, Shihezi, Xinjiang Uyghur Autonomous Region, China.ORCID 0000-0001-7881-8644
Shihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental dyslexia is a complex reading and writing disorder with strong genetic components. In previous genetic studies about dyslexia, a number of candidate genes have been identified. These include DCDC2, which has repeatedly been associated with developmental dyslexia in various European and American populations. However, data regarding this relationship are varied according to population. The Uyghur people of China represent a Eurasian population with an interesting genetic profile. Thus, this group may provide useful information about the association between DCDC2 gene polymorphisms and dyslexia. In the current study, we examined genetic data from 392 Uyghur children aged 8-12 years old from the Xinjiang Uyghur Autonomous Region of China. Participants included 196 children with dyslexia and 196 grade-, age-, and gender-matched controls. DNA was isolated from oral mucosal cell samples and fourteen single nucleotide polymorphisms (rs6456593, rs1419228, rs34647318, rs9467075, rs793862, rs9295619, rs807701, rs807724, rs2274305, rs7765678, rs4599626, rs6922023, rs3765502, and rs1087266) in DCDC2 were screened

Indexed as

case-control studydevelopmental dyslexiaelementary school studentsetiologygene polymorphismsgeneticsnerve regenerationneural regenerationreading disabilitysingle nucleotide polymorphismsXinjiang Uyghur Autonomous Region

Identifiers

PMID28400808
PMCPMC5361510
OpenAlexW2589645461

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.