Evidence map›Paper›PMID 28400768›Full record

ArticleFrontiers in microbiology2017

The Anti-helminthic Compound Mebendazole Has Multiple Antifungal Effects against

Luna S Joffe, Rafael Schneider, William Lopes, Renata Azevedo, Charley C Staats, Lívia Kmetzsch, Augusto Schrank, Maurizio Del Poeta, Marilene H Vainstein, Marcio L Rodrigues

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 82 citations in OpenAlex.

  1. Virulence · 2026
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  2. Cellular and molecular responses ofMicrobiology spectrum · 2026
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  3. Article
  4. Review
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  6. Article
  7. Insights from Mass Spectrometry-Based Proteomics onJournal of fungi (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Growth of nematophagous fungi in the presence of anthelmintics drugs.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  10. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Luna S JoffeLaboratório de Biologia Celular de Leveduras Patogênicas, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil.
Rafael SchneiderCentro de Biotecnologia, Universidade Federal do Rio Grande do Sul Porto Alegre, Brazil.
William LopesCentro de Biotecnologia, Universidade Federal do Rio Grande do Sul Porto Alegre, Brazil.
Renata AzevedoFundação Oswaldo Cruz - Fiocruz, Centro de Desenvolvimento Tecnológico em Saúde Rio de Janeiro, Brazil.
Charley C StaatsCentro de Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil; Departamento de Biologia Molecular e Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil.
Lívia KmetzschCentro de Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil; Departamento de Biologia Molecular e Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil.
Augusto SchrankCentro de Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil; Departamento de Biologia Molecular e Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil.
Maurizio Del PoetaVeterans Administration Medical Center, NorthportNY, USA; Department of Molecular Genetics and Microbiology, Stony Brook University, Stony BrookNY, USA.
Marilene H VainsteinCentro de Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil; Departamento de Biologia Molecular e Biotecnologia, Universidade Federal do Rio Grande do SulPorto Alegre, Brazil.
Marcio L RodriguesLaboratório de Biologia Celular de Leveduras Patogênicas, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de JaneiroRio de Janeiro, Brazil; Fundação Oswaldo Cruz - Fiocruz, Centro de Desenvolvimento Tecnológico em SaúdeRio de Janeiro, Brazil.
Universidade Federal do Rio Grande do Sul · BRFundação Oswaldo Cruz · BRStony Brook University · USUniversidade Federal do Rio de Janeiro · BR

Funding

New antifungals targeting the synthesis of fungal sphingolipidsR01AI116420 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI Maurizio Del Poeta · 2016 to 2026
$7.6M
Lipid-mediated fungal pathogenesisR01AI125770 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2016 to 2025
$6.2M
Sphingosine-1-phosphate and cryptococcosisR01AI136934 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2018 to 2022
$2.5M
NIAID NIH HHS R01 AI116420NIAID NIH HHS R01 AI125770NIAID NIH HHS R01 AI136934Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antifungalantifungal targetsbenzimidazolesbiofilmCryptococcus neoformansmacrophagesmebendazole

Identifiers

PMID28400768
PMCPMC5368277
OpenAlexW2601070101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.