Evidence map›Paper›PMID 28400735›Full record

ArticleFrontiers in physiology2017

A Novel Stopped-Flow Assay for Quantitating Carbonic-Anhydrase Activity and Assessing Red-Blood-Cell Hemolysis.

Pan Zhao, R Ryan Geyer, Walter F Boron

Abstract read
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Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Role of channels in thebioRxiv : the preprint server for biology · 2025
    Article
  2. Role of channels in the ObioRxiv : the preprint server for biology · 2025
    Article
  3. Extracellular carbonic anhydrase activity promotes a carbon concentration mechanism in metazoan calcifying cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Carbonic anhydrase and soluble adenylate cyclase regulation of cystic fibrosis cellular phenotypes.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Carbonic anhydrases as disease markers.Expert opinion on therapeutic patents · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pan ZhaoDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine Cleveland, OH, USA.
R Ryan GeyerDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine Cleveland, OH, USA.
Walter F BoronDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a novel carbonic-anhydrase (CA) assay and its use for quantitating red-blood-cell (RBC) lysis during stopped-flow (SF) experiments. We combine two saline solutions, one containing HEPES/pH 7.03 and the other, ~1% CO

Indexed as

acid-based balancebicarbonatecarbon dioxideout-of-equilibrium solutionsphenol redpH-sensitive dyespyranine

Identifiers

PMID28400735
PMCPMC5368281

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.