Evidence map›Paper›PMID 28400575›Full record

ArticleThe Journal of antibiotics2017

Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli.

Gergana A Vandova, Robert V O'Brien, Brian Lowry, Thomas F Robbins, Curt R Fischer, Ronald W Davis, Chaitan Khosla, Colin Jb Harvey, Maureen E Hillenmeyer

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of antibiotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. EngineeringMetabolic engineering communications · 2025
    Article
  2. Article
  3. Article
  4. Heterologous Expression of Secondary Metabolite Genes inJournal of fungi (Basel, Switzerland) · 2022
    Article
  5. EngineeringJournal of fungi (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gergana A VandovaStanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.
Robert V O'BrienDepartment of Chemistry, Stanford University, Stanford, CA,USA.
Brian LowryDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.
Thomas F RobbinsDepartment of Chemistry, Stanford University, Stanford, CA,USA.
Curt R FischerStanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.
Ronald W DavisStanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.
Chaitan KhoslaDepartment of Chemistry, Stanford University, Stanford, CA,USA.
Colin Jb HarveyStanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.
Maureen E HillenmeyerStanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.
Stanford University · USCardiovascular Institute of the South · US

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI DAVIS, RONALD WAYNE, HOWE, ROGER THOMAS · 1990 to 2016
$120.9M
Genomic and synthetic biology tools for expressing natural product gene clustersU01GM110706 · NIGMS · STANFORD UNIVERSITY · PI DAVIS, RONALD WAYNE, STEINMETZ, LARS M · 2014 to 2018
$10.9M
Structure, Mechanism, and Engineering of Assembly Line Polyketide SynthasesR01GM087934 · NIGMS · STANFORD UNIVERSITY · PI KHOSLA, CHAITAN · 2009 to 2021
$4.9M
NHGRI NIH HHS P01 HG000205NIGMS NIH HHS R01 GM087934NIGMS NIH HHS U01 GM110706
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Escherichia coliGene Expression Regulation, EnzymologicMethylmalonyl-CoA DecarboxylasePolyketidesPolyketide SynthasesMethylmalonyl-CoA DecarboxylasePolyketidesPolyketide Synthases

Identifiers

PMID28400575
PMCPMC5509990
OpenAlexW2605503123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.