Evidence map›Paper›PMID 28400459›Full record

ArticleBMJ open2017

Investigating the relationship between precocious puberty and obesity: a cross-sectional study in Shanghai, China.

Chang Chen, Yunting Zhang, Wanqi Sun, Yao Chen, Yanrui Jiang, Yuanjin Song, Qinmin Lin, Lixia Zhu, Qi Zhu, Xiumin Wang and 2 more

Erratum issued Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04113070 (The Effect of Childhood Overweight and Obesity and Genetic Factors on Puberty Development), which is not on this map. Cited by 54 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 6 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04113070 recruitingnot on this mapstarted 2019, after this paper: background citation

The Effect of Childhood Overweight and Obesity and Genetic Factors on Puberty Development: a Prospective Cohort Study

TypeobservationalSponsorShanghai Jiao Tong University School of MedicineRan2019 to 2026Enrolled14,100ConditionsPrecocious Puberty, Overweight and ObesityArmsAnthropometric measuring, Growth environment evaluation
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 6 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Chang ChenSchool of Public Health, Shanghai Jiao Tong University, Shanghai, China.
Yunting ZhangChild Health Advocacy Institute, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wanqi SunDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yao ChenShanghai Key Laboratory of Children's Environmental Health, Shanghai Jiaotong University School of Medicine Xinhua Hospital, Shanghai, China.
Yanrui JiangDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuanjin SongDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Qinmin LinDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lixia ZhuDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Qi ZhuDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiumin WangDepartment of Endocrine and Genetic Metabolic Diseases, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Shijian LiuSchool of Public Health, Shanghai Jiao Tong University, Shanghai, China liushijian@scmc.com.cn.ORCID 0000-0002-7050-463X
Fan JiangShanghai Key Laboratory of Children's Environmental Health, Shanghai Jiaotong University School of Medicine Xinhua Hospital, Shanghai, China.
Shanghai Children's Medical Center · CNXinHua Hospital · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesObesity is reported to be closely relevant to early sexual development but the relationship between sexual precocity and obesity or central obesity is still inconsistent, especially in boys. We aimed to investigate the relationship between precocious puberty and obesity as well as central obesity.

designA large population-based cross-sectional study using multistage, stratified cluster random sampling.

settingData from the Shanghai Children's Health, Education and Lifestyle Evaluation (SCHEDULE) study in June 2014.

participants17 620 Chinese children aged 6-12 years. PRIMARY AND SECONDARY OUTCOME MEASURES: Obesity was defined by WHO Child Growth Standards. Central obesity was defined by sex-specific waist-to-height ratio (WHtR) cut-offs (WHtR ≥0.48 for boys, WHtR ≥0.46 for girls). Precocious puberty was identified by Tanner stage of breast, pubic hair and testicle development. A χ

results25.98% and 38.58% of boys with precocious puberty were respectively accompanied by obesity (OR=2.15, 95% CI=1.31 to 3.50) or central obesity (OR=2.10, 95% CI=1.46 to 3.03); meanwhile, 13.86% and 29.42% of girls with precocious puberty were respectively accompanied by obesity (OR=9.00, 95% CI=5.60 to 14.46) or central obesity (OR=5.40, 95% CI=4.10 to 7.12). The median ages of breast, pubic hair and testicle development decreased with BMI increase and median ages of thelarche and testicular development rather than pubarche were earlier in children with central obesity.

conclusionsEarlier pubertal development was positively associated with obesity and central obesity in Chinese children.

Indexed as

Body Mass IndexChildChinaCross-Sectional StudiesFemaleHumansMaleObesityObesity, AbdominalOdds RatioPrevalencePuberty, PrecociousSex DistributionWaist-Height RatioEPIDEMIOLOGYObesityPAEDIATRICSPuberty

Identifiers

PMID28400459
PMCPMC5566589
OpenAlexW2606989374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.