Evidence map›Paper›PMID 28400443›Full record

ArticleThe Journal of cell biology2017

Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis.

Wei Yung Ding, Hui Ting Ong, Yusuke Hara, Jantana Wongsantichon, Yusuke Toyama, Robert C Robinson, François Nédélec, Ronen Zaidel-Bar

Abstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei Yung DingMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.
Hui Ting OngMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.
Yusuke HaraMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0002-2005-7704
Jantana WongsantichonInstitute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology, and Research), Singapore 138673, Singapore.ORCID 0000-0002-4134-2248
Yusuke ToyamaMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0003-3230-1062
Robert C RobinsonInstitute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology, and Research), Singapore 138673, Singapore.
François NédélecCell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.ORCID 0000-0002-8141-5288
Ronen Zaidel-BarMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0002-1374-5007

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

The cell cortex is essential to maintain animal cell shape, and contractile forces generated within it by nonmuscle myosin II (NMY-2) drive cellular morphogenetic processes such as cytokinesis. The role of actin cross-linking proteins in cortical dynamics is still incompletely understood. Here, we show that the evolutionarily conserved actin bundling/cross-linking protein plastin is instrumental for the generation of potent cortical actomyosin contractility in the

Indexed as

Cell PolarityCytokinesisActinsActomyosinAnimalsCaenorhabditis elegansCell ShapeMembrane GlycoproteinsMicrofilament ProteinsMorphogenesisTime FactorsZygoteActinsActomyosinMembrane GlycoproteinsMicrofilament Proteinsplastin

Identifiers

PMID28400443
PMCPMC5412556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.