Evidence map›Paper›PMID 28400428›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck Cancer.

Sonja Ludwig, Theofanis Floros, Marie-Nicole Theodoraki, Chang-Sook Hong, Edwin K Jackson, Stephan Lang, Theresa L Whiteside

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 236 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
236citing papers in PubMed, 1 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

236 citing papers in PubMed, 1 synthesis or guideline pooled it, 334 citations in OpenAlex.

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176 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sonja LudwigDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Theofanis FlorosDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Marie-Nicole TheodorakiUniversity of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Chang-Sook HongDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Edwin K JacksonDepartment of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Stephan LangDepartment of Otorhinolaryngology, University of Duisburg-Essen, Germany.
Theresa L WhitesideDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. whitesidetl@upmc.edu.
UPMC Hillman Cancer Center · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Restoring anti-tumor immunity in the microenvironment of head and neck cancerR01CA168628 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHITESIDE, THERESA L. · 2013 to 2017
$1.7M
(PQ11) Reversing exosome-mediated immune suppression - a novel strategy for cancer therapyR21CA205644 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYIADZIS, MICHAEL, WHITESIDE, THERESA L. · 2016 to 2017
$370k
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA168628NCI NIH HHS R21 CA205644
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedApoptosisCell ProliferationCoculture TechniquesExosomesFemaleHead and Neck NeoplasmsHumansKiller Cells, NaturalLymphocyte ActivationMaleMiddle AgedT-LymphocytesT-Lymphocytes, RegulatoryYoung Adult

Identifiers

PMID28400428
PMCPMC5559308
OpenAlexW2605377619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.