Evidence map›Paper›PMID 28399823›Full record

ArticleBMC infectious diseases2017

Alcohol use disorders among people living with HIV/AIDS in Southern Brazil: prevalence, risk factors and biological markers outcomes.

Cláudio Moss da Silva, Raúl Andrés Mendoza-Sassi, Luisa Dias da Mota, Maíba Mikhael Nader, Ana Maria Barral de Martinez

Abstract read
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In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  15. HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cláudio Moss da SilvaFaculty of Medicine, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil. cmossdasilva@gmail.com.
Raúl Andrés Mendoza-SassiFaculty of Medicine, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil.
Luisa Dias da MotaFaculty of Medicine, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil.
Maíba Mikhael NaderFaculty of Medicine, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil.
Ana Maria Barral de MartinezFaculty of Medicine, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol abuse is an important public health problem, frequently unrecognized among people living with HIV/AIDS (PLWHA), and requires investigation and intervention. It is usually associated with lower adherence to highly active antiretroviral therapy (HAART). It can also produce adverse clinical outcomes, such as changes in certain HIV markers, particularly CD4 cell counts and HIV viral loads (VLs). Thus, this study aimed to evaluate the prevalence of alcohol abuse among PLWHA, its associated risk factors and effects on CD4 cell counts and HIV VLs in southern Brazil.

methodsBetween December 2012 and July 2013, 343 patients were interviewed at a reference hospital in southern Brazil. The instrument used was the Alcohol Use Disorder Identification Test (AUDIT), and a cutoff of eight points or more was applied. Socioeconomic, demographic, clinical and laboratory data were also collected. The statistical analysis included a Poisson regression to evaluate the factors associated with alcohol use disorder, and a linear regression was performed to assess the relationship between AUDIT scores and CD4 cell counts and HIV VLs.

resultsAlcohol abuse was present in 28.6% of the respondents, and possible dependence was present in 5%. The risk factors identified included being male, mixed or black skin color, low education and the use of intravenous or inhaled drugs. A higher AUDIT score was associated with a lower CD4 cell count but was not associated with higher HIV VL values.

conclusionsOur results show the importance of screening for alcohol abuse in this group. The prevalence of alcohol abuse was high, and it was associated with socioeconomic factors and the use of illicit drugs. Moreover, AUDIT score negatively affected CD4 cell counts as well.

Indexed as

Acquired Immunodeficiency SyndromeAdolescentAdultAgedAlcoholismAntiretroviral Therapy, Highly ActiveBiomarkersBrazilCD4 Lymphocyte CountFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRisk FactorsBiomarkersAlcohol induced disordersBrazilHIV/AidsImmunologic markersPrevalenceRisk factors

Identifiers

PMID28399823
PMCPMC5387222

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.