Evidence map›Paper›PMID 28399821›Full record

ArticleBMC medical research methodology2017

Comparison of surveillance-based metrics for the assessment and monitoring of disease detection: simulation study about type 2 diabetes.

Ralph Brinks, Annika Hoyer, Deborah B Rolka, Oliver Kuss, Edward W Gregg

Abstract read
In one paragraph

Article in BMC medical research methodology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ralph BrinksGerman Diabetes Center, Leibniz Institute for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Institute for Biometry and Epidemiology, Auf'm Hennekamp 65, Düsseldorf, 40225, Germany. Ralph.Brinks@ddz.uni-duesseldorf.de.
Annika HoyerGerman Diabetes Center, Leibniz Institute for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Institute for Biometry and Epidemiology, Auf'm Hennekamp 65, Düsseldorf, 40225, Germany.
Deborah B RolkaCenters for Disease Control and Prevention, Division of Diabetes Translation, Atlanta, Georgia, USA.
Oliver KussGerman Diabetes Center, Leibniz Institute for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Institute for Biometry and Epidemiology, Auf'm Hennekamp 65, Düsseldorf, 40225, Germany.
Edward W GreggCenters for Disease Control and Prevention, Division of Diabetes Translation, Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScreening and detection of cases are a common public health priority for treatable chronic conditions with long subclinical periods. However, the validity of commonly-used metrics from surveillance systems for rates of detection (or case-finding) have not been evaluated.

methodsUsing data from a Danish diabetes register and a recently developed illness-death model of chronic diseases with subclinical conditions, we simulate two scenarios of different performance of case-finding. We report different epidemiological indices to assess case-finding in both scenarios and compare the validity of the results.

resultsThe commonly used ratio of detected cases over total cases may lead to misleading conclusions. Instead, the ratio of undetected cases over persons without a diagnosis is a more valid index to distinguish the quality of case-finding. However, incidence-based measures are preferable to prevalence based indicators.

conclusionPrevalence-based indices for assessing case-finding should be interpreted with caution. If possible, incidence-based indices should be preferred.

Indexed as

Chronic DiseaseDenmarkDiabetes Mellitus, Type 2HumansMaleMass ScreeningCase-findingChronic diseaseCompartment modelDiabetesIncidencePrevalenceScreeningUndiagnosed disease

Identifiers

PMID28399821
PMCPMC5387346

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