ArticlePloS one2017
Mild Traumatic Brain Injury (mTBI) and chronic cognitive impairment: A scoping review.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 250 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Different Courses of Change in Connectivity After mTBI Depending on Cognitive Reserve and How This is Related to Symptoms and Symptom Resolution?
Direct Current Transcranial Stimulation as Cognitive Rehabilitation Therapy in Post-Traumatic Brain Injury Patients.
Boosting Brain and Balance: A Mobile Dual-Task Intervention for Athletes With Concussion and Mild Traumatic Brain Injury (mTBI)
Who cites it
250 citing papers in PubMed, 8 syntheses or guidelines pooled it, 492 citations in OpenAlex.
- Traumatic brain injury among American indians/alaska natives in the united states: a comprehensive systematic review of the literature.Neurosurgical review · 2025Pooled it
- Association of overt hypothyroidism with risks of cognitive impairment: a meta-analysis and systematic review.Frontiers in endocrinology · 2025Pooled it
- Diffusion-Weighted Imaging in Mild Traumatic Brain Injury: A Systematic Review of the Literature.Neuropsychology review · 2023Pooled it
- A Systematic Review of ASL Perfusion MRI in Mild TBI.Neuropsychology review · 2023Pooled it
- Traumatic brain injury in Brazil: an epidemiological study and systematic review of the literature.Arquivos de neuro-psiquiatria · 2022Pooled it
- An Interplay Between Post-Traumatic Epilepsy and Associated Cognitive Decline: A Systematic Review.Frontiers in neurology · 2022Pooled it
- Systematic Review and Dosage Analysis: Hyperbaric Oxygen Therapy Efficacy in Mild Traumatic Brain Injury Persistent Postconcussion Syndrome.Frontiers in neurology · 2022Pooled it
- The More, the Better: High-Dose Omega-3 Fatty Acids Improve Behavioural and Molecular Outcomes in Preclinical Models in Mild Brain Injury.Current neurology and neuroscience reports · 2021Pooled it
- Feasibility of Using a Mobile App Supported Executive Function Intervention in Military Service Members and Veterans with mTBI and Co-Occurring Psychological Conditions.International journal of environmental research and public health · 2023Trial
- Trial
- Role of Polygenic Risk Scores in Predicting Cognitive Functioning after Mild Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma · 2026Article
- Mild and repetitive mild traumatic brain injury: Changes in microglial cells and synapses.Neural regeneration research · 2026Article
- Serum neutrophil extracellular trap-related biomarkers for identifying cognitive impairment after mild traumatic brain injury.Irish journal of medical science · 2026Article
- Safety and Changes in Health-Related Quality of Life After Epidural Oxygen Injection for Long COVID/Post-COVID Syndrome: A Multicenter Retrospective Study.Journal of clinical medicine · 2026Article
- Resting-State Brain Entropy Reveals Altered Neural Dynamics and Cognitive Associations in Mild Traumatic Brain Injury: A Longitudinal Study.Journal of neuroscience research · 2026Article
- Gabapentin and cognitive impairment after traumatic brain injury: A multinational cohort of 49,925 patients.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Long-Term Mortality and Quality of Life Among Adults With Mild Traumatic Brain Injury.JAMA network open · 2026Article
- Injury Severity Influences Long-Term Cognitive Control in Pediatric "Mild" Traumatic Brain Injury.Human brain mapping · 2026Article
- Pervasive TBI and Inhibitory Control in a Male New Zealand Prison Population.Brain sciences · 2026Article
- Spatiotemporal modeling of tau aggregation following traumatic brain injury: implications for chronic traumatic encephalopathy.Biomechanics and modeling in mechanobiology · 2026Article
190 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mild traumatic brain injury (mTBI), or concussion, is the most common type of traumatic brain injury. With mTBI comes symptoms that include headaches, fatigue, depression, anxiety and irritability, as well as impaired cognitive function. Symptom resolution is thought to occur within 3 months post-injury, with the exception of a small percentage of individuals who are said to experience persistent post-concussion syndrome. The number of individuals who experience persistent symptoms appears to be low despite clear evidence of longer-term pathophysiological changes resulting from mTBI. In light of the incongruency between these longer-term changes in brain pathology and the number of individuals with longer-term mTBI-related symptoms, particularly impaired cognitive function, we performed a scoping review of the literature that behaviourally assessed short- and long-term cognitive function in individuals with a single mTBI, with the goal of identifying the impact of a single concussion on cognitive function in the chronic stage post-injury. CINAHL, Embase, and Medline/Ovid were searched July 2015 for studies related to concussion and cognitive impairment. Data relating to the presence/absence of cognitive impairment were extracted from 45 studies meeting our inclusion criteria. Results indicate that, in contrast to the prevailing view that most symptoms of concussion are resolved within 3 months post-injury, approximately half of individuals with a single mTBI demonstrate long-term cognitive impairment. Study limitations notwithstanding, these findings highlight the need to carefully examine the long-term implications of a single mTBI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.