Evidence map›Paper›PMID 28399137›Full record

ArticlePloS one2017

The importance of choice disability and structural intervention in the HIV epidemic in Sub-Saharan Africa.

Rebecca de Boer, Jeffrey Musgrave, Neil Andersson, Frithjof Lutscher

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rebecca de BoerDepartment of Mathematics and Statistics, University of Ottawa, Ottawa, Ontario, Canada.
Jeffrey MusgraveDepartment of Mathematics and Statistics, University of Ottawa, Ottawa, Ontario, Canada.
Neil AnderssonDepartment of Family Medicine, McGill University, Montreal, Quebec, Canada.
Frithjof LutscherDepartment of Mathematics and Statistics, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0001-7380-7647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite massive investment in HIV control programs, HIV incidence rates in countries with generalized epidemics have not fallen for most of the last decade. It appears that those at risk are not adopting effective prevention strategies. Those who are unable to implement their prevention preferences are referred to as choice disabled. We examined how and to what extent structural intervention measures that support choice-disabled individuals can reduce HIV transmission and prevalence.

methodsA mathematical model was developed to describe HIV transmission among and between choice-disabled and choice-enabled individuals. Data were available from field trials identifying factors and effects of choice disability. The model was used to estimate the potential impact of an intervention strategy in which choice-disabled individuals are enabled to make prevention choices. Several scenarios were considered and compared: supporting only one or both genders; supporting only HIV- individuals or also HIV+ choice-disabled individuals.

resultsSubstantial declines in HIV incidence and prevalence are observed when supportive interventions are included in the model. The magnitude of these declines depends on the scope of the intervention program. The largest positive effect occurs when the support program is offered regardless of HIV status.

conclusionsAddressing the effects of choice disability in any HIV intervention program could be crucial to the program's success. Structural intervention programs to support choice-disabled individuals in implementing prevention strategies greatly reduce HIV incidence and prevalence in mathematical models.

Indexed as

Choice BehaviorAfrica South of the SaharaFemaleHIV InfectionsHumansMale

Identifiers

PMID28399137
PMCPMC5388482

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.