Trial reportPediatric research2017
Feasibility and physiological effects of noninvasive neurally adjusted ventilatory assist in preterm infants.
Trial report in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04000568 (Breathing Pattern Variability in Preterm Infants), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Breathing Pattern Variability in Preterm Infants: Effect of Non-invasive Neurally Adjusted Ventilatory Assist (NAVA-NIV) Versus Nasal Intermittent Positive Pressure Ventilation (PC-NIV), a Crossover Study
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Triggering modalities to synchronise non-invasive respiratory support in preterm infants: a systematic review and meta-analysis.BMJ paediatrics open · 2026Pooled it
- NIV-NAVA versus non-invasive respiratory support in preterm neonates: a meta-analysis of randomized controlled trials.Journal of perinatology : official journal of the California Perinatal Association · 2024Pooled it
- Monitoring the patient-ventilator asynchrony during non-invasive ventilation.Frontiers in medicine · 2022Pooled it
- Diaphragm-triggered non-invasive respiratory support in preterm infants.The Cochrane database of systematic reviews · 2020Pooled it
- Perspectives of medical staff on respiratory management with neurally adjusted ventilatory assist in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- The Effect of Body Position on Oxygenation, Ventilation, and Diaphragmatic Workload in Infants Born Premature on Noninvasive Neurally Adjusted Ventilatory Assist.Journal of pediatrics. Clinical practice · 2026Article
- Efficacy of Noninvasive Neurally Adjusted Ventilatory Assist (NIV-NAVA) for Neonates With Transient Tachypnea of the Newborn: A Retrospective Analysis.Pediatric pulmonology · 2025Article
- Non-Invasive Ventilation with Neurally Adjusted Ventilatory Assist (NAVA) Improves Extubation Outcomes in Extremely Low-Birth-Weight Infants.Children (Basel, Switzerland) · 2024Article
- Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) in the neonatal intensive care unit (NICU): an Australian NICU experience.BMC pediatrics · 2024Article
- Optimizing Invasive Neonatal Respiratory Care: A Systematic Review of Invasive Neurally Adjusted Ventilatory Assist.Healthcare (Basel, Switzerland) · 2024Review
- Noninvasive Neurally Adjusted Ventilation versus Nasal Continuous or Intermittent Positive Airway Pressure for Preterm Infants: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2023Review
- Effects of heliox and non-invasive neurally adjusted ventilatory assist (NIV-NAVA) in preterm infants.Scientific reports · 2021Article
- Non-Invasive Ventilatory Strategies to Decrease Bronchopulmonary Dysplasia-Where Are We in 2021?Children (Basel, Switzerland) · 2021Review
- Evaluating peak inspiratory pressures and tidal volume in premature neonates on NAVA ventilation.European journal of pediatrics · 2021Article
- "Current concepts in assisted mechanical ventilation in the neonate" - Part 2: Understanding various modes of mechanical ventilation and recommendations for individualized disease-based approach in neonates.International journal of pediatrics & adolescent medicine · 2020Review
- Randomized Longitudinal Study Comparing Three Nasal Respiratory Support Modes to Prevent Intermittent Hypoxia in Very Preterm Infants.Children (Basel, Switzerland) · 2020Article
- A Review on Non-invasive Respiratory Support for Management of Respiratory Distress in Extremely Preterm Infants.Frontiers in pediatrics · 2020Review
- Precision Medicine in Neonates: Future Perspectives for the Lung.Frontiers in pediatrics · 2020Review
- Comparison of NIV-NAVA and NCPAP in facilitating extubation for very preterm infants.BMC pediatrics · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
BackgroundNoninvasive neurally adjusted ventilator assist (NIV-NAVA) was introduced to our clinical practice via a pilot and a randomized observational study to assess its safety, feasibility, and short-term physiological effects.MethodsThe pilot protocol applied NIV-NAVA to 11 infants on nasal CPAP, high-flow nasal cannula, or nasal intermittent mandatory ventilation (NIMV), in multiple 2- to 4-h periods of NIV-NAVA for comparison. This provided the necessary data to design a randomized, controlled observational crossover study in eight additional infants to compare the physiological effects of NIV-NAVA with NIMV during 2-h steady-state conditions. We recorded the peak inspiratory pressure (PIP), FiO
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