Evidence map›Paper›PMID 28399114›Full record

ArticlePediatric research2017

Lung hypoplasia in newborn rabbits with a diaphragmatic hernia affects pulmonary ventilation but not perfusion.

Andreas W Flemmer, Marta Thio, Megan J Wallace, Katie Lee, Marcus J Kitchen, Lauren Kerr, Charles C Roehr, Andreas Fouras, Richard Carnibella, Jaccques C Jani and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Andreas W FlemmerDivision of Neonatology University Children's Hospital and Perinatal Center, Ludwig Maximilian University, Munich, Germany.
Marta ThioNewborn Research Centre, The Royal Women's Hospital, Melbourne, Australia.
Megan J WallaceRitchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Katie LeeSchool of Physics and Astronomy, Monash University, Melbourne, Australia.
Marcus J KitchenSchool of Physics and Astronomy, Monash University, Melbourne, Australia.
Lauren KerrRitchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Charles C RoehrRitchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Andreas FourasDepartment of Mechanical and Aerospace Engineering, Monash University, Melbourne, Australia.
Richard CarnibellaSchool of Physics and Astronomy, Monash University, Melbourne, Australia.
Jaccques C JaniDepartment of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Philip DeKoninckRitchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Arjan B Te PasDivision of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
James T PearsonMonash Biomedical Imaging Facility, Department of Physiology, Monash University, Melbourne, Australia.
Stuart B HooperRitchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Monash University · AUHudson Institute of Medical Research · AULeiden University Medical Center · NLLudwig-Maximilians-Universität München · DEUniversité Libre de Bruxelles · BEUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundA congenital diaphragmatic hernia (DH) can result in severe lung hypoplasia that increases the risk of morbidity and mortality after birth; however, little is known about the cardiorespiratory transition at birth.MethodsUsing phase-contrast X-ray imaging and angiography, we examined the cardiorespiratory transition at birth in rabbit kittens with DHs. Surgery was performed on pregnant New Zealand white rabbits (n=18) at 25 days' gestation to induce a left-sided DH. Kittens were delivered at 30 days' gestation, intubated, and ventilated to achieve a tidal volume (V

Indexed as

Pulmonary VentilationAnimalsAnimals, NewbornFemaleHernias, Diaphragmatic, CongenitalLungPregnancyRabbitsRegional Blood FlowTidal Volume

Identifiers

PMID28399114
PMCPMC5605670
OpenAlexW2607436471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.