Evidence map›Paper›PMID 28398703›Full record

ArticleBirth defects research2017

Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California.

Amy M Padula, Wei Yang, Suzan L Carmichael, Frederick Lurmann, John Balmes, S Katharine Hammond, Gary M Shaw

Abstract read
In one paragraph

Article in Birth defects research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hypospadias Risk from Maternal Residential Exposure to Heavy Metal Hazardous Air Pollutants.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amy M PadulaUniversity of California, San Francisco, San Francisco, California.
Wei YangStanford University, Stanford, California.
Suzan L CarmichaelStanford University, Stanford, California.
Frederick LurmannUniversity of California, Berkeley, Berkeley, California.
John BalmesUniversity of California, San Francisco, San Francisco, California.
S Katharine HammondSonoma Technology, Inc, Petaluma, California.
Gary M ShawStanford University, Stanford, California.

Funding

UC Berkeley/Stanford Children's Enviromental Health CenterP01ES022849 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R · 2013 to 2018
$4.2M
Project 3: Ambient Pollutants/Bioaerosol Effects on Treg FunctionP20ES018173 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAGER, IRA B · 2010 to 2012
$895k
Traffic-related Air Pollution, Social Factors and Adverse Birth OutcomesR00ES021470 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PADULA, AMY MICHELLE · 2016 to 2018
$746k
Traffic-related air pollution, social factors and adverse birth outcomesK99ES021470 · NIEHS · STANFORD UNIVERSITY · PI PADULA, AMY MICHELLE · 2013 to 2014
$254k
NIEHS NIH HHS K99 ES021470NIEHS NIH HHS L40 ES023163NIEHS NIH HHS P01 ES022849NIEHS NIH HHS P20 ES018173NIEHS NIH HHS R00 ES021470
6 · The paper itself

Abstract

backgroundNeural tube defects (NTDs) are one of the most common types of birth defects. Environmental pollutants and acculturation have been associated with NTDs independently. The potential effect modification of acculturation in the relationship between ambient air pollution and risks of NTDs is not well understood.

methodsWe investigated whether associations between traffic-related air pollutant exposure in early gestation and NTDs, and more specifically spina bifida, were modified by individual and neighborhood acculturation factors among 139 cases and 466 controls born in the San Joaquin Valley of California, 1997 to 2006. Five criteria pollutant exposures in tertiles, two outcomes, and seven neighborhood acculturation factors from the U.S. Census at the block group level were included for a total of 280 investigated associations. Estimates were adjusted for maternal education and multivitamin use in the first 2 months of pregnancy. Additional analyses were stratified by nativity.

resultsIncreased odds of NTDs were observed for individuals who had high exposures to carbon monoxide, nitrogen oxide, or nitrogen dioxide and lived in neighborhoods that were more acculturated. Conversely, there were increased odds of NTDs for those who had high prenatal exposure to PM

conclusionNeighborhood acculturation factors were modifiers of the relationship between air pollution and NTDs in California, though not in a consistent direction for all pollutants. Birth Defects Research 109:403-422, 2017. © 2017 Wiley Periodicals, Inc.

Indexed as

AcculturationAdultAir PollutantsAir PollutionCaliforniaCarbon MonoxideCase-Control StudiesEnvironmental ExposureFemaleHispanic or LatinoHumansMaternal ExposureNeural Tube DefectsParticulate MatterPregnancyPrenatal Exposure Delayed EffectsAir PollutantsCarbon MonoxideParticulate Matteracculturationair pollutionbirth outcomescongenital anomalies

Identifiers

PMID28398703
PMCPMC5773251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.