Evidence map›Paper›PMID 28398508›Full record

SynthesisRheumatology (Oxford, England)2017

Examining the validity of the rheumatoid arthritis magnetic resonance imaging score according to the OMERACT filter-a systematic literature review.

Thasia G Woodworth, Olga Morgacheva, Olga L Pimienta, Orrin M Troum, Veena K Ranganath, Daniel E Furst

Registry-linked trialOpen access · bronzeAbstract readSystematic ReviewValidation Study
In one paragraph

Synthesis in Rheumatology (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05657847 (Novel Complex Radiodiagnostics of Peripherial Arthropathies), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05657847 recruitingnot on this mapstarted 2022, after this paper: background citation

Novel Complex Radiodiagnostics of Peripherial Arthropathies

TypeobservationalSponsorSemmelweis UniversityRan2022 to 2027Enrolled500ConditionsArthritis, Rheumatoid, Arthritis, Psoriatic, Crystal ArthropathiesArmsPhoton-counting detector-CT
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. MRI of synovitis and joint fluid.Journal of magnetic resonance imaging : JMRI · 2019
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thasia G WoodworthDepartment of Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles.
Olga MorgachevaDepartment of Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles.
Olga L PimientaKeck School of Medicine, University of Southern California, Santa Monica, CA, USA.
Orrin M TroumKeck School of Medicine, University of Southern California, Santa Monica, CA, USA.
Veena K RanganathDepartment of Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles.
Daniel E FurstDepartment of Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles.
University of California, Los Angeles · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine whether the RA MRI score (RAMRIS) for RA of the wrist/hand meets the OMERACT filter criteria-truth (validity), discrimination and feasibility. Methods: We conducted a systematic literature review in PubMed and Scopus, from 1970 through June 2014, focused on MRI measures of synovitis, osteitis/bone marrow oedema, erosions and/or joint space narrowing in RA randomized controlled trials and observational studies with cohort size ⩾10. Strength of evidence was assessed using the Cochrane Handbook criteria. Results: Of 634 MRI titles/abstracts, 202 met the review criteria, with 92 providing at least 1 type of validity. Four articles provided criterion validity, and 26 articles utilized RAMRIS to assess 1.5 T MRI images. Histopathology data showed inflammation corresponding to MRI of synovitis and osteitis. MRI erosions corresponded to those identified with CT. Content and construct validity for RAMRIS synovitis, osteitis and erosions were documented by correlations with clinical, laboratory and/or radiographic data. Each measure was sensitive to change and responsive to therapy. RAMRIS synovitis and osteitis were able to discriminate between the efficacy of treatments vs placebo in 12-week studies, whereas RAMRIS erosions required studies of ⩾24 weeks. Conclusion: RAMRIS synovitis, osteitis and erosions imaged with 1.5 T MRI are valid and useful for evaluating joint inflammation and damage for RA of the wrist/hand, according to the OMERACT filter.

Indexed as

AgedAntirheumatic AgentsArthritis, RheumatoidFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedObserver VariationRetrospective StudiesTreatment OutcomeAntirheumatic Agentsclinical trialsmagnetic resonance imagingMRIOMERACT filterRAMRISrheumatoid arthritisrheumatoid arthritis magnetic resonance imaging scorestructural progression

Identifiers

PMID28398508
PMCPMC5850856
OpenAlexW2604997963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.