Evidence map›Paper›PMID 28398340›Full record

ArticleTranslational psychiatry2017

The impact of common dopamine D2 receptor gene polymorphisms on D2/3 receptor availability: C957T as a key determinant in putamen and ventral striatum.

C T Smith, L C Dang, J W Buckholtz, A M Tetreault, R L Cowan, R M Kessler, D H Zald

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Review
  3. An Interactive Brain Atlas of Knowledge.bioRxiv : the preprint server for biology · 2026
    Article
  4. Substantial Heritability Underlies Fairness Norm Adaptation Capability and its Neural Basis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
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  14. Article
  15. Article
  16. Review
  17. Article
  18. Individual differences in dopamine DCognitive, affective & behavioral neuroscience · 2018
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

C T SmithDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
L C DangDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
J W BuckholtzDepartment of Psychology, Harvard University, Cambridge, MA, USA.
A M TetreaultDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
R L CowanDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
R M KesslerDepartment of Radiology, UAB School of Medicine, Birmingham, AL, USA.
D H ZaldDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · USHarvard University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Transgenerational epigenetic inheritance of longevityDP1AG044848 · NIA · STANFORD UNIVERSITY · PI BRUNET, ANNE · 2012 to 2016
$3.9M
Individual Differences in Extrastriatal DA ReleaseR01DA019670 · NIDA · VANDERBILT UNIVERSITY · PI ZALD, DAVID HAROLD · 2006 to 2009
$1.3M
Dopamine Influences on Self-Regulation and ImpulsivityR21DA033611 · NIDA · VANDERBILT UNIVERSITY · PI ZALD, DAVID HAROLD · 2011 to 2012
$367k
Radiofluorination Equipment for PET Imaging ResearchS10OD019963 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2016 to 2016
$291k
Linking Temporal Differences in d-Amphetamine Subjective Effects to DRD2 and DATF32DA041157 · NIDA · VANDERBILT UNIVERSITY · PI SMITH, CHRISTOPHER THOMAS · 2016 to 2018
$174k
Dopamine function in reward-driven decision makingF32DA036979 · NIDA · VANDERBILT UNIVERSITY · PI DANG, LINH CAT · 2015 to 2017
$173k
NCATS NIH HHS UL1 TR000445NIA NIH HHS DP1 AG044848NIDA NIH HHS F32 DA036979NIDA NIH HHS F32 DA041157NIDA NIH HHS R01 DA019670NIDA NIH HHS R21 DA033611
6 · The paper itself

Abstract

Dopamine function is broadly implicated in multiple neuropsychiatric conditions believed to have a genetic basis. Although a few positron emission tomography (PET) studies have investigated the impact of single-nucleotide polymorphisms (SNPs) in the dopamine D2 receptor gene (DRD2) on D2/3 receptor availability (binding potential, BP

Indexed as

AllelesAdolescentAdultBenzamidesDopamineFemaleFluorine RadioisotopesGenetic DeterminismGenetic LinkageGenotypeHumansImage Interpretation, Computer-AssistedMalePolymorphism, Single NucleotidePositron-Emission TomographyPutamenBenzamidesDopamineDRD2 protein, humanDRD3 protein, humanfallyprideFluorine-18Fluorine RadioisotopesReceptors, Dopamine D2Receptors, Dopamine D3

Identifiers

PMID28398340
PMCPMC5416688
OpenAlexW2607431938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.