Evidence map›Paper›PMID 28398134›Full record

ArticleCulture, health & sexuality2017

'I told her this is your life': relationship dynamics, partner support and adherence to antiretroviral therapy among South African couples.

Amy Conroy, Anna Leddy, Mallory Johnson, Thulani Ngubane, Heidi van Rooyen, Lynae Darbes

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Culture, health & sexuality, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04906616 nacompletednot on this mapstarted 2021, after this paper: background citation

An Economic and Relationship-strengthening Intervention for HIV-affected Couples Who Drink Alcohol in Malawi

TypeinterventionalSponsorUniversity of California, San FranciscoRan2021 to 2023Enrolled156ConditionsHIV/AIDS, Alcohol AbuseArmsMlambe
NCT06367348 narecruitingnot on this mapstarted 2025, after this paper: background citation

Mlambe: A Randomized Controlled Trial of an Economic and Relationship-Strengthening Intervention to Reduce Alcohol Use in Malawi

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2028Enrolled500ConditionsHIV/AIDS, Alcohol AbuseArmsMlambe
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.

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  10. "AIDS care · 2026
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  18. Managing multimorbidity together: relationship dynamics and dual medication adherence for hypertension and HIV in Malawi.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Amy Conroya Center for AIDS Prevention Studies , University of California , San Francisco , USA.
Anna Leddyb Department of Health, Behavior and Society , John Hopkins University , Baltimore , USA.
Mallory Johnsona Center for AIDS Prevention Studies , University of California , San Francisco , USA.
Thulani Ngubanec Human and Social Development Program , Human Sciences Research Council , Msunduzi , South Africa.
Heidi van Rooyend Human and Social Development , Human Sciences Research Council , Overport , South Africa.
Lynae Darbese Department of Health Behavior and Biological Sciences , University of Michigan , Ann Arbor , USA.
Human Sciences Research Council · ZAJohns Hopkins University · USSan Francisco AIDS Foundation · USUniversity of California, San Francisco · USUniversity of Michigan–Ann Arbor · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Relationship Factors and Engagement in HIV Care in Malawi: A Dyadic InvestigationK01MH107331 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2016 to 2019
$773k
NIAID NIH HHS P30 AI027763NIDA NIH HHS K24 DA037034NIMH NIH HHS K01 MH107331NIMH NIH HHS T32 MH019105
6 · The paper itself

Abstract

Despite the important role of social relationships for health and wellbeing, little is known about how primary partners affect adherence to HIV care and treatment. We qualitatively explored how relationship dynamics and partner support influence adherence among couples from KwaZulu-Natal, South Africa. Twenty-four heterosexual couples with at least one HIV-positive partner completed semi-structured interviews on topics including relationship dynamics (intimacy or emotional closeness, communication, violence), experiences with HIV care and treatment and HIV-related social support. The majority of couples were seroconcordant HIV-positive (92%) and both on antiretroviral therapy (ART) (63%). Participants described how primary partners both interfered with and supported adherence. Negative forms of influence included relationship conflict, which resulted in forgetfulness to take pills, and men's attempt to control use of ART. However, participants were more likely to highlight positive forms of influence on adherence, which included social support (instrumental, informational and emotional), intimacy and commitment. The findings also suggest a reciprocal relationship between ART and relationships such that couple ART use may enhance relationship quality. Primary partners are important pillars of support for ART adherence, especially in contexts of high unemployment and poverty. Future interventions that encourage and leverage these supportive relationships could improve ART adherence among heterosexual couples in similar settings.

Indexed as

Medication AdherenceSocial SupportAdultAnti-Retroviral AgentsBlack PeopleFemaleHIV InfectionsHumansMaleSexual PartnersSouth AfricaSurveys and QuestionnairesAnti-Retroviral Agentsantiretroviral therapycouplesRelationship dynamicssocial supportSouth Africa

Identifiers

PMID28398134
PMCPMC5626574
OpenAlexW2606420103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.