Evidence map›Paper›PMID 28398068›Full record

ArticleAIDS research and human retroviruses2017

Restoring Cytokine Balance in HIV-Positive Individuals with Low CD4 T Cell Counts.

Anddre Valdivia, Judy Ly, Leslie Gonzalez, Parveen Hussain, Tommy Saing, Hicret Islamoglu, Daniel Pearce, Cesar Ochoa, Vishwanath Venketaraman

Open access · bronzeAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Effects of Oral Liposomal Glutathione in Altering the Immune Responses AgainstFrontiers in cellular and infection microbiology · 2021
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Review
  9. Glutathione in HIV-Associated Neurocognitive Disorders.Current issues in molecular biology · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anddre Valdivia1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Judy Ly1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Leslie Gonzalez1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Parveen Hussain1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Tommy Saing1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Hicret Islamoglu3 Department of Biological Sciences, California State Polytechnic University , Pomona, California.
Daniel Pearce4 Riverside University Health System , Public Health, Early Intervention/HIV, Riverside, California.
Cesar Ochoa6 Western Diabetes Institute, Western University of Health Sciences , Pomona, California.
Vishwanath Venketaraman1 Graduate College of Biomedical Sciences, Western University of Health Sciences , Pomona, California.
Western University of Health Sciences · USCalifornia State Polytechnic University · USLoma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV infects and destroys CD4+ T cells leading to a compromised immune system. In a double-blinded study, a group of HIV-infected individuals with CD4+ T cell counts below 350 cells/mm

Indexed as

AdultAgedCD4 Lymphocyte CountCD4-Positive T-LymphocytesCytokinesFemaleHIV InfectionsHumansInterferon-gammaInterleukinsMaleMiddle AgedTransforming Growth Factor betaCytokinesInterferon-gammaInterleukinsTransforming Growth Factor betaAIDScytokinesglutathioneHIVredox homeostasis

Identifiers

PMID28398068
PMCPMC5576219
OpenAlexW2606839449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.