Evidence map›Paper›PMID 28397883›Full record

ArticleNanoscale2017

Chemical and mechanical modulation of polymeric micelle assembly.

Nicholas E Clay, Joseph J Whittenberg, Jiayu Leong, Vivek Kumar, Jinrong Chen, Insil Choi, Evangelos Liamas, Jeremy M Schieferstein, Jae Hyun Jeong, Dong Hyun Kim and 4 more

Abstract read
In one paragraph

Article in Nanoscale, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Engineering Polymersomes for Diagnostics and Therapy.Advanced healthcare materials · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Nicholas E ClayDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, 61801 USA. hjkong06@illinois.edu.
Joseph J Whittenberg
Jiayu Leong
Vivek Kumar
Jinrong Chen
Insil Choi
Evangelos Liamas
Jeremy M Schieferstein
Jae Hyun Jeong
Dong Hyun Kim
Zhenyu Jason Zhang
Paul J A Kenis
Il Won Kim
Hyunjoon Kong
University of Illinois Urbana-Champaign · USSoongsil University · KRUniversity of Birmingham · GBKorea Institute of Industrial Technology · KR

Funding

Nanocells for vascular normalization therapiesR01HL109192 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2011 to 2015
$1.9M
Development of a Liposomal Nanostimulator to Improve Stem Cell-Based Revascularization TherapiesR21HL131469 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2016 to 2017
$428k
NHLBI NIH HHS R01 HL109192NHLBI NIH HHS R21 HL131469
6 · The paper itself

Abstract

Recently, polymeric micelles self-assembled from amphiphilic polymers have been studied for various industrial and biomedical applications. This nanoparticle self-assembly typically occurs in a solvent-exchange process. In this process, the quality of the resulting particles is uncontrollably mediated by polymeric solubility and mixing conditions. Here, we hypothesized that improving the solubility of an amphiphilic polymer in an organic solvent via chemical modification while controlling the mixing rate of organic and aqueous phases would enhance control over particle morphology and size. We examined this hypothesis by synthesizing a poly(2-hydroxyethyl)aspartamide (PHEA) grafted with controlled numbers of octadecyl (C

Identifiers

PMID28397883
PMCPMC5501961
OpenAlexW2607390640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.