Evidence map›Paper›PMID 28397558›Full record

ArticleThe Annals of otology, rhinology, and laryngology2017

Measurement of Cough Aerodynamics in Healthy Adults.

Aaron J Feinstein, Zhaoyan Zhang, Dinesh K Chhetri, Jennifer Long

Open access · greenAbstract read
In one paragraph

Article in The Annals of otology, rhinology, and laryngology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aaron J Feinstein1 Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Zhaoyan Zhang1 Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Dinesh K Chhetri1 Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Jennifer Long1 Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · US

Funding

Neuromuscular control of the LarynxR01DC011300 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHHETRI, DINESH KHATRI · 2011 to 2021
$6.0M
Biomechanical Mechanisms of PhonationR01DC011299 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZHAOYAN · 2011 to 2015
$2.4M
Bilayered Vocal Fold Tissue EngineeringIK2BX001944 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI LONG, JENNIFER L · 2013 to 2017
–
BLRD VA IK2 BX001944NIDCD NIH HHS R01 DC011299NIDCD NIH HHS R01 DC011300
6 · The paper itself

Abstract

importanceCough is a critical human reflex and also among the most frequent symptoms in medicine. Despite the prevalence of disordered cough in laryngeal pathologies, comprehensive and quantitative evaluation of cough in these patients is lacking.

objectiveHerein we seek to establish normative values for cough aerodynamics to provide a population standard for reference in future studies. DESIGN, SETTING, AND

participantsHealthy subjects were recruited from an outpatient clinic to perform voluntary cough. Subjects were instructed on the technique for maximal voluntary cough production with measurements recorded on pneumotachograph. Fifty-two subjects were studied, including 29 women and 23 men with a mean age of 51.6 and 52.3 years, respectively. Main Outcomes and Measures: Cough peak airflow, peak pressure, and expiratory rise time. Results were stratified by age, gender, and height.

resultsPeak airflow demonstrated significant differences across age, gender, and height, with flow increasing according to increasing height. Peak cough pressure also increased with height and was significantly greater in males versus females. Expiratory rise time, the time from glottal opening to peak airflow, did not vary with age or height but was statistically significantly longer in women.

conclusionsCough aerodynamics can be readily measured objectively in the outpatient setting. Expiratory rise time, peak flow, and peak pressure are important aspects of each cough epoch. Normative data provided herein can be used for future studies of patients with laryngotracheal disorders, and these cough parameters may prove to be simple, accessible, and repeatable outcome measures.

Indexed as

Respiratory Physiological PhenomenaAdultAge FactorsCoughFemaleHumansMaleMiddle AgedPeak Expiratory Flow RateReference ValuesRespiratory Function TestsSex Factorsaspiration pneumoniacoughlaryngeal diseaseslaryngologyrespiratory function testsrespiratory tract diseases

Identifiers

PMID28397558
PMCPMC10241208
OpenAlexW2592353326

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.