Evidence map›Paper›PMID 28397372›Full record

ArticleJournal of neuroscience research2017

K channel impairment determines sex and age differences in epinephrine-mediated outcomes after brain injury.

William M Armstead, John Riley, Monica S Vavilala

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Cerebral microcirculatory alterations and the no-reflow phenomenon in vivo after experimental pediatric cardiac arrest.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

William M ArmsteadDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia.ORCID 0000-0002-3241-801X
John RileyDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia.
Monica S VavilalaDepartment of Anesthesiology, Pediatrics, and Neurological Surgery, and Harborview Injury Prevention and Research Center, University of Washington, Seattle.ORCID 0000-0002-4210-8066
University of Pennsylvania · USUniversity of the Sciences · USUniversity of Washington · US

Funding

Pressor Choice Influences Protection Of Autoregulation in Brain InjuryR01NS090998 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ARMSTEAD, WILLIAM M · 2015 to 2019
$1.8M
NINDS NIH HHS R01 NS090998
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is the leading cause of injury-related death in children, with boys and children under 4 years having particularly poor outcomes. Activation of ATP- and calcium-sensitive (K

Indexed as

Age FactorsAnimalsBrain Injuries, TraumaticCerebrovascular CirculationEpinephrineFemaleMalePotassium ChannelsRandom AllocationSex CharacteristicsSwineVasodilationVasodilator AgentsEpinephrinePotassium ChannelsVasodilator AgentsautoregulationKATP, KCa channelspressor supporttraumatic brain injury

Identifiers

PMID28397372
PMCPMC5561463
OpenAlexW2606829848

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.