ArticleJournal of materials science. Materials in medicine2017
Electrospun silk fibroin-gelatin composite tubular matrices as scaffolds for small diameter blood vessel regeneration.
Article in Journal of materials science. Materials in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Silk Fibroin Hydrogels: Cutting-edge Developments and Future Directions.Pharmaceutical nanotechnology · 2026Review
- Current Strategies for Engineered Vascular Grafts and Vascularized Tissue Engineering.Polymers · 2023Review
- Glycosaminoglycans: From Vascular Physiology to Tissue Engineering Applications.Frontiers in chemistry · 2021Review
- Bioresorbable Polymeric Scaffold in Cardiovascular Applications.International journal of molecular sciences · 2020Review
- Wavy small-diameter vascular graft made of eggshell membrane and thermoplastic polyurethane.Materials science & engineering. C, Materials for biological applications · 2020Article
- Electrospun fibers and their application in drug controlled release, biological dressings, tissue repair, and enzyme immobilization.RSC advances · 2019Review
- Steady-State Behavior and Endothelialization of a Silk-Based Small-Caliber Scaffold In Vivo Transplantation.Polymers · 2019Article
- Current Strategies for the Manufacture of Small Size Tissue Engineering Vascular Grafts.Frontiers in bioengineering and biotechnology · 2018Review
- Blood vessels bioengineered from induced pluripotent stem cell derived mesenchymal stem cells and porous silk fibroin coated functional scaffolds.Journal of tissue engineeringArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this work an innovative method to obtain natural and biocompatible small diameter tubular structures is proposed. The biocompatibility and good mechanical properties of electrospun silk fibroin tubular matrices (SFts), extensively studied for tissue engineering applications, have been coupled with the excellent cell interaction properties of gelatin. In fact, an innovative non-cytotoxic gelatin gel, crosslinked in mild conditions via a Michael-type addition reaction, has been used to coat SFt matrices and obtain SFt/gel structures (I.D. = 6 mm). SFts/gel exhibited homogeneous gelatin coating on the electrospun fibrous tubular structure. Circumferential tensile tests performed on SFts/gel showed mechanical properties comparable to those of natural blood vessels in terms of UTS, compliance and viscoelastic behavior. Finally, SFt/gel in vitro cytocompatibility was confirmed by the good viability and spread morphology of L929 fibroblasts up to 7 days. These results demonstrated that SFt/gel is a promising off-the-shelf graft for small diameter blood vessel regeneration.
Indexed as
Identifiers
28397163What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.