Evidence map›Paper›PMID 28397152›Full record

ArticleMetabolic brain disease2017

Neuroprotective effect of Moringa oleifera leaf extract on aluminium-induced temporal cortical degeneration.

Moses B Ekong, Mfon M Ekpo, Edet O Akpanyung, Dennis U Nwaokonko

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
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  18. Nutritional Value ofNutrients · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Moses B EkongDepartment of Anatomy, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria. mbe_flashpoint@yahoo.com.
Mfon M EkpoDepartment of Anatomy, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria.
Edet O AkpanyungDepartment of Biochemistry, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria.
Dennis U NwaokonkoDepartment of Biochemistry, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria.
University of Uyo · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aluminium (Al), one of the metals implicated in neurodegeneration easily gain access to the nervous system through its presence in many manufactured foods, medicines and drinking water, and causes neurotoxicity utilizing the reactive oxygen specie pathway. The need to curtail these effects on the nervous system motivated the use of the plant Moringa oleifera (MO). This study thus, investigated the neuroprotective effects of MO leaf extract on aluminium-induced temporal cortical degeneration in rats. 24 male albino Wistar rats were grouped (n = 6) into control (1 ml/kg distilled water), l00 mg/kg aluminium chloride (AlCl

Indexed as

AluminumAluminum ChlorideAluminum CompoundsAnimalsAtrophyChloridesGlial Fibrillary Acidic ProteinLethal Dose 50MaleMoringa oleiferaNerve DegenerationNeuroprotective AgentsNeurotoxicity SyndromesPhosphopyruvate HydratasePlant ExtractsPlant LeavesAluminumAluminum ChlorideAluminum CompoundsChloridesGfap protein, ratGlial Fibrillary Acidic ProteinNeuroprotective AgentsPhosphopyruvate HydratasePlant ExtractsAluminiumImmunolabellingMoringa oleiferaNeurodegenerationNeuroprotection

Identifiers

PMID28397152
OpenAlexW2607072858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.