Evidence map›Paper›PMID 28397132›Full record

ReviewCurrent gastroenterology reports2017

Modifiable Environmental Factors in Inflammatory Bowel Disease.

Kristin E Burke, Christine Boumitri, Ashwin N Ananthakrishnan

Abstract readReview
In one paragraph

Review in Current gastroenterology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. The specialized educational and psychological counseling in inflammatory bowel disease patients - a target or a challenge?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
    Trial
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  11. The Antioxidant and Anti-Inflammatory Effects ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  12. Secondary causes of inflammatory bowel diseases.World journal of gastroenterology · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Environmental triggers in IBD: a review of progress and evidence.Nature reviews. Gastroenterology & hepatology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristin E BurkeDivision of Gastroenterology, Massachusetts General Hospital, Boston, USA.
Christine BoumitriDivision of Gastroenterology, University of Missouri-Columbia, Columbia, USA.
Ashwin N AnanthakrishnanDivision of Gastroenterology, Massachusetts General Hospital, Boston, USA. aananthakrishnan@mgh.harvard.edu.

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3M
Genetic predictors of anti-TNF treatment response and infections in IBDK23DK097142 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ANANTHAKRISHNAN, ASHWIN N · 2012 to 2016
$846k
NIDDK NIH HHS K23 DK097142NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

purpose of reviewEnvironmental factors may influence predisposition to develop inflammatory bowel diseases (Crohn's disease, ulcerative colitis) or alter its natural history by modification of both the host immune response and intestinal microbial composition. The purpose of this review is to translate such evidence into clinical practice by a focus on interventional studies that have modified such environmental influences to improve disease outcomes. RECENT

findingsSeveral environmental influences have been identified in the recent literature including tobacco use, diet, antibiotics, vitamin D deficiency, stress, appendectomy, and oral contraceptive use. Some risk factors have similar influences on both Crohn's disease and ulcerative colitis while others are disease-specific or have divergent effects. Emerging epidemiologic evidence has confirmed the association of many of these factors with incident disease using prospective data. In addition, laboratory data has supported their mechanistic plausibility and relevance to intestinal inflammation.

Indexed as

EnvironmentDietDietary SupplementsEnteral NutritionHumansInflammatory Bowel DiseasesRisk FactorsSleep Wake DisordersSmokingStress, PsychologicalCrohn’s diseaseDietEnvironmentSmokingUlcerative colitis

Identifiers

PMID28397132
PMCPMC5651146

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.