Evidence map›Paper›PMID 28396990›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2017

Incidence and outcomes of early left ventricular thrombus following ST-elevation myocardial infarction treated with primary percutaneous coronary intervention.

Shafik Khoury, Sarit Carmon, Gilad Margolis, Gad Keren, Yacov Shacham

Abstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Long-term effects of device-guided slow breathing in stable heart failure patients with reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
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  5. Contemporary incidence and predictors of left ventricular thrombus in patients with anterior acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
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  13. Polyhedral erythrocytes in intracoronary thrombus and their association with reperfusion in myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
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  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shafik KhouryThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Shafik.khoury@gmail.com.
Sarit CarmonThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Gilad MargolisThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Gad KerenThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yacov ShachamThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · ILTel Aviv Sourasky Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the advent of primary percutaneous coronary intervention (PCI), studies have reported a declining incidence of left ventricular thrombus (LVT) following ST-elevation myocardial infarction (STEMI). We investigated the incidence and outcomes of early (pre-discharge) LVT in the contemporary era of PCI practice in a large cohort of STEMI patients.

methodsWe retrospectively studied 2071 consecutive STEMI patients who underwent successful primary PCI. Screening echocardiography was performed within 24-48 h of admission. Patients with anterior STEMI were treated with intravenous heparin for 24-48 h until a first echocardiography test was performed. Patients with reduced ejection fraction (EF) ≤40% had a repeat test before hospital discharge (days 5-7). Heparin was continued in case of significant left ventricular dysfunction (EF < 35%) or apical akinesis or dyskinesis, until a second test ruled out LVT.

resultsLVT was diagnosed before hospital discharge in 31/2071 patients (1.5%), 28 of whom (90%) had anterior STEMI. Only 2/31 patients with LVT (6.5%) developed embolic events before discharge and 1/31 (3.2%) had an episode of upper gastrointestinal bleeding that required blood transfusion. There was no significant difference between the two groups regarding in-hospital STEMI-related complications, short- and long-term mortality. All LVTs resolved in subsequent echocardiograms within 6 months of discharge.

conclusionsWe report a low incidence of early LVT following STEMI. Further studies are needed to assess the efficacy and safety of a limited in-hospital anticoagulation protocol in STEMI patients with reduced EF.

Indexed as

AgedAnticoagulantsEchocardiographyFemaleGastrointestinal HemorrhageHeparinHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionRetrospective StudiesST Elevation Myocardial InfarctionThrombosisTime FactorsVentricular Dysfunction, LeftAnticoagulantsHeparinAnticoagulation following STEMILeft ventricular thrombusPrimary percutaneous coronary interventionST-elevation myocardial infarction

Identifiers

PMID28396990
OpenAlexW2605381935

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.