Evidence map›Paper›PMID 28396941›Full record

ArticlePediatric nephrology (Berlin, Germany)2017

Effect of the timing of dialysis initiation on left ventricular hypertrophy and ınflammation in pediatric patients.

Sevcan A Bakkaloğlu, Yaşar Kandur, Erkin Serdaroğlu, Aytül Noyan, Aysun Karabay Bayazıt, Lale Sever, Sare Gülfem Özlü, Gül Özçelik, İsmail Dursun, Caner Alparslan

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Should we abandon GFR in the decision to initiate chronic dialysis?Pediatric nephrology (Berlin, Germany) · 2020
    Review
  5. Article
  6. Assessment and management of fluid overload in children on dialysis.Pediatric nephrology (Berlin, Germany) · 2019
    Review
  7. Assessment of dialysis adequacy: beyond urea kinetic measurements.Pediatric nephrology (Berlin, Germany) · 2019
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sevcan A BakkaloğluDepartment of Pediatric Nehprology, School of Medicine, Gazi University, Ankara, Turkey. sevcan@gazi.edu.tr.
Yaşar KandurDepartment of Pediatric Nehprology, School of Medicine, Gazi University, Ankara, Turkey.
Erkin SerdaroğluDepartment of Pediatric Nephrology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Aytül NoyanDepartment of Pediatric Nehprology, School of Medicine, Başkent University, Adana, Turkey.
Aysun Karabay BayazıtDepartment of Pediatric Nephrology, School of Medicine, Çukurova University, Adana, Turkey.
Lale SeverDepartment of Pediatric Nephrology, Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey.
Sare Gülfem ÖzlüDepartment of Pediatric Nephrology, Dr.Sami Ulus Maternity and Children Research and Training Hospital, Ankara, Turkey.
Gül ÖzçelikDepartment of Pediatric Nephrology, Şişli Etfal Training and Research Hospital, Istanbul, Turkey.
İsmail DursunDepartment of Pediatric Nehprology, School of Medicine, Erciyes University, Kayseri, Turkey.
Caner AlparslanDepartment of Pediatric Nephrology, Tepecik Training and Research Hospital, İzmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal time for dialysis initiation in adults and children with chronic kidney disease remains unclear. The aim of this study was to evaluate the impact of dialysis timing on different outcome parameters, in particular left ventricular (LV) morphology and inflammation, in pediatric patients receiving peritoneal dialysis and hemodialysis.

methodsThe medical records of pediatric dialysis patients who were followed-up in nine pediatric nephrology centers in Turkey between 2008 and 2013 were retrospectively reviewed. In addition to demographic data, we retrieved anthropometric measurements, data on dialysis treatment modalities, routine biochemical parameters, complete blood count, serum ferritin, parathormone, C-reactive protein (CRP), and albumin levels, as well as echocardiographic data and hospitalization records. The patients were divided into two groups based on their estimated glomerular filtration rate (eGFR) levels at dialysis initiation, namely, an early-start group, characterized by an eGFR of >10 ml/min/1.73 m

resultsA total of 245 pediatric dialysis patients (mean age ± standard deviation 12.3 ± 5.1 years, range 0.5-21 years) were enrolled in this study. Echocardiographic data were available for 137 patients, and the mean LV mass index (LVMI) was 58 ± 31 (range 21-215) g/m

conclusionAlthough early dialysis initiation did not have a significant effect on important clinical outcome parameters, including LVH, inflammatory state, and hospitalization, in our pediatric dialysis patients, this area of study deserves further attention.

Indexed as

Time-to-TreatmentAdolescentAdultChildChild, PreschoolEchocardiographyFemaleGlomerular Filtration RateHospitalizationHumansHypertrophy, Left VentricularInfantKidney Failure, ChronicMalePeritoneal DialysisRenal DialysisChildrenEarly dialysisGlomerular filtration rateLate dialysisLeft ventricular hypertrophy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.