Evidence map›Paper›PMID 28396751›Full record

ArticleClinical case reports2017

An abscopal effect in a case of concomitant treatment of locally and peritoneally recurrent gastric cancer using adoptive T-cell immunotherapy and radiotherapy.

Hiro Sato, Yoshiyuki Suzuki, Yuya Yoshimoto, Shin-Ei Noda, Kazutoshi Murata, Yosuke Takakusagi, Atsushi Okazaki, Tetsuo Sekihara, Takashi Nakano

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03453164 (Combination of Checkpoint Inhibitor and Radiotherapy for Recurrent Gastric Cancer After Initial Treatment With Standard Therapy), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03453164 phase1 / phase2completednot on this mapstarted 2018, after this paper: background citation

Combination of Checkpoint Inhibitor and Radiotherapy for Recurrent Gastric Cancer After Initial Treatment With Standard Therapy (CIRCUIT).

TypeinterventionalSponsorFukushima Medical UniversityRan2018 to 2021Enrolled41ConditionsGastric CancerArmsRadiotherapy, Nivolumab
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  7. Abscopal effect in the radio and immunotherapy.Radiation oncology journal · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hiro SatoDepartment of Radiation Oncology Gunma University Graduate School of Medicine Maebashi Japan.
Yoshiyuki SuzukiDepartment of Radiation Oncology Fukushima Medical University Fukushima Japan.
Yuya YoshimotoDepartment of Radiation Oncology Gunma University Graduate School of Medicine Maebashi Japan.
Shin-Ei NodaDepartment of Radiation Oncology Gunma University Graduate School of Medicine Maebashi Japan.
Kazutoshi MurataDepartment of Radiation Oncology Gunma University Graduate School of Medicine Maebashi Japan.
Yosuke TakakusagiOncology Center Hidaka Hospital Takasaki Japan.
Atsushi OkazakiDepartment of Radiation Oncology Tsuboi Cancer Center Hospital Koriyama Japan.
Tetsuo SekiharaDepartment of Urology Hidaka Hospital Takasaki Japan.
Takashi NakanoDepartment of Radiation Oncology Gunma University Graduate School of Medicine Maebashi Japan.
Gunma University · JPHidaka Hospital · JPFukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanism of abscopal effect is becoming clear by the progress of cancer immunology. A 54-year-old male with recurrent gastric cancer presented an abscopal effect after radiotherapy with concurrent adoptive T-cell immunotherapy (immunoradiotherapy). Immunoradiotherapy has potential to induce abscopal effect by strengthening systemic antitumor immunity even in recurrent cancer.

Indexed as

Abscopal effectadoptive T‐cell immunotherapygastric cancerperitoneal disseminationradiotherapy

Identifiers

PMID28396751
PMCPMC5378826
OpenAlexW2588437507

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.