Evidence map›Paper›PMID 28396728›Full record

ArticleWorld journal of radiology2017

Computed tomography pulmonary angiography using a 20% reduction in contrast medium dose delivered in a multiphasic injection.

Mitchell Chen, Gaith Mattar, Jamal A Abdulkarim

Abstract read
In one paragraph

Article in World journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mitchell ChenMitchell Chen, Jamal A Abdulkarim, Department of Radiology, George Eliot Hospital NHS Trust, Nuneaton, Warwickshire CV10 7DJ, United Kingdom.
Gaith MattarMitchell Chen, Jamal A Abdulkarim, Department of Radiology, George Eliot Hospital NHS Trust, Nuneaton, Warwickshire CV10 7DJ, United Kingdom.
Jamal A AbdulkarimMitchell Chen, Jamal A Abdulkarim, Department of Radiology, George Eliot Hospital NHS Trust, Nuneaton, Warwickshire CV10 7DJ, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the feasibility of reducing the dose of iodinated contrast agent in computed tomography pulmonary angiography (CTPA).

methodsOne hundred and twenty-seven patients clinically suspected of having pulmonary embolism underwent spiral CTPA, out of whom fifty-seven received 75 mL and the remaining seventy a lower dose of 60 mL of contrast agent. Both doses were administered in a multiphasic injection. A minimum opacification threshold of 250 Hounsfield units (HU) in the main pulmonary artery is used for assessing the technical adequacy of the scans.

resultsMean opacification was found to be positively correlated to patient age (Pearson's correlation 0.4255,

conclusionA lower dose of iodine contrast at 60 mL can be feasibly used in CTPA without resulting in a higher number of sub-optimally opacified scans.

Indexed as

Acute kidney diseaseComputed tomography pulmonary angiographyContrast doseContrast dose reductionContrast induced nephropathyContrast safetyMultiphasic injection

Identifiers

PMID28396728
PMCPMC5368630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.