ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2017
Nasal nitric oxide in allergic rhinitis in children and its relationship to severity and treatment.
Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Nasal nitric oxide measurement in allergic rhinitis and non-allergic rhinitis: a meta-analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024Pooled it
- Nasal nitric oxide testing for allergic rhinitis patients: Systematic review and meta-analysis.Immunity, inflammation and disease · 2021Pooled it
- Nasal Nitric Oxide as an Objective Evaluation Tool for Treatment Response in Chronic Rhinitis.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025Article
- Application of fractional exhaled nitric oxide and nasal nitric oxide in the evaluation of asthma control.Frontiers in pediatrics · 2025Article
- Nasal Nitric Oxide in Children: A Review of Current Outreach in Pediatric Respiratory Medicine.Children (Basel, Switzerland) · 2023Review
- Clinical Applications of Nasal Nitric Oxide in Allergic Rhinitis: A Review of the Literature.Journal of clinical medicine · 2023Review
- [Study on nasal nitric oxide concentrations of 50 healthy individuals in Dalian].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- Clinical application of fractional exhaled nitric oxide and nasal nitric oxide levels for the assess eosinophilic inflammation of allergic rhinitis among children.Translational pediatrics · 2021Article
- The Role of Nasal Nitric Oxide and Anterior Active Rhinomanometry in the Diagnosis of Allergic Rhinitis and Asthma: A Message for Pediatric Clinical Practice.Journal of asthma and allergy · 2021Article
- Nasal Nitric Oxide Is Correlated With Nasal Patency and Nasal Symptoms.Allergy, asthma & immunology research · 2019Article
- Nasal nitric oxide is a useful biomarker for acute unilateral maxillary sinusitis in pediatric allergic rhinitis: A prospective observational cohort study.The World Allergy Organization journal · 2019Article
- [Usefulness of measurement of nitric oxide in exhaled air in diagnostics and treatment of allergic rhinitis and asthma in children and adolescents].Developmental period medicineReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNasal nitrous oxide (nNO) is increased in allergic rhinitis (AR), but not in asthma, and is a non-invasive marker for inflammation in the nasal passages.
methodsLevels of nNO were measured and compared in healthy children and children with mild and moderate-to-severe AR. Levels of nNO before and after treatment with steroids and/or antihistamine were then compared in the 2 AR groups. Their relationship to quality of life and nasal symptom and reactivity to outdoor and outdoor allergens were examined.
resultsnNO levels were higher in mild AR than in healthy children and higher in moderate-to-severe AR than in mild AR. One month steroid and/or antihistamine treatment lowered nNO levels to control levels in mild AR and approximately halfway to control levels in moderate-to-severe AR. nNO levels had a weak correlation to quality of life questions and a fair correlation to nasal symptom scores before treatment. This correlation was weakened or lost after treatment, and no correlation was seen between nNO levels and responses to indoor or outdoor allergens.
conclusionnNO levels in children with AR may be useful for assessing the response to treatment. Their relationship to quality of life, nasal symptoms, and sensitivity to specific allergens needs further study.
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