Evidence map›Paper›PMID 28396668›Full record

ArticleFrontiers in immunology2017

Extracellular Vesicles Mediate Radiation-Induced Systemic Bystander Signals in the Bone Marrow and Spleen.

Tünde Szatmári, Dávid Kis, Enikő Noémi Bogdándi, Anett Benedek, Scott Bright, Deborah Bowler, Eszter Persa, Enikő Kis, Andrea Balogh, Lívia N Naszályi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. From Genome to Geroscience: How DNA Damage Shapes Systemic Decline.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  5. Article
  6. Irradiation alters extracellular vesicle microRNA load in the serum of patients with leukaemia.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  7. Extracellular vesicles role in radio(nuclide)therapy.Journal of radiation research · 2024
    Review
  8. Effect of radiotherapy on the DNA cargo and cellular uptake mechanisms of extracellular vesicles.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Review
  9. Low-Dose Non-Targeted Effects and Mitochondrial Control.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Radiation-induced liver disease: beyond DNA damage.Cell cycle (Georgetown, Tex.) · 2023
    Review
  13. The emerging role of exosomes in radiotherapy.Cell communication and signaling : CCS · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Emerging roles for AQP in mammalian extracellular vesicles.Biochimica et biophysica acta. Biomembranes · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Tünde SzatmáriDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Dávid KisDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Enikő Noémi BogdándiDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Anett BenedekDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Scott BrightGenomic Instability Group, Department of Biological and Medical Sciences, Oxford Brookes University , Oxford , UK.
Deborah BowlerGenomic Instability Group, Department of Biological and Medical Sciences, Oxford Brookes University , Oxford , UK.
Eszter PersaDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Enikő KisDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Andrea BaloghDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Lívia N NaszályiResearch Group for Molecular Biophysics, Hungarian Academy of Sciences, Semmelweis University , Budapest , Hungary.
Munira KadhimGenomic Instability Group, Department of Biological and Medical Sciences, Oxford Brookes University , Oxford , UK.
Géza SáfrányDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Katalin LumniczkyDivision of Radiation Medicine, National Public Health Centre, National Research Directorate for Radiobiology and Radiohygiene , Budapest , Hungary.
Frédéric Joliot-Curie National Research Institute for Radiobiology and Radiohygiene · HUOxford Brookes University · GBHungarian Academy of Sciences · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation-induced bystander effects refer to the induction of biological changes in cells not directly hit by radiation implying that the number of cells affected by radiation is larger than the actual number of irradiated cells. Recent

Indexed as

bystander effectsextracellular vesicleshematopoietic systemionizing radiationmicroRNA

Identifiers

PMID28396668
PMCPMC5366932
OpenAlexW2602541598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.