Evidence map›Paper›PMID 28396548›Full record

ArticleAntimicrobial agents and chemotherapy2017

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia.

Wan Jung Kim, Keith A Korthals, Suhua Li, Christine Le, Jarosław Kalisiak, K Barry Sharpless, Valery V Fokin, Yukiko Miyamoto, Lars Eckmann

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wan Jung KimDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Keith A KorthalsDepartment of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Suhua LiDepartment of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Christine LeDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Jarosław KalisiakDepartment of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
K Barry SharplessDepartment of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Valery V FokinDepartment of Chemistry, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, USA.
Yukiko MiyamotoDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Lars EckmannDepartment of Medicine, University of California, San Diego, La Jolla, California, USA leckmann@ucsd.edu.
Scripps Research Institute · USUniversity of California, San Diego · USUniversity of Southern California · US

Funding

Next-generation 5-nitro heterocyclic antimicrobials against mucosal protistsR01AI114671 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ECKMANN, LARS · 2015 to 2019
$3.1M
Click chemistry for novel antimicrobials against periodontal pathogensRC1DE020607 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ECKMANN, LARS, FOKIN, VALERY V · 2009 to 2010
$962k
NIAID NIH HHS R01 AI114671NIDCR NIH HHS RC1 DE020607
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Infective AgentsAntiprotozoal AgentsClick ChemistryGiardia lambliaNitrofuransParasitic Sensitivity TestsPyrrolesStructure-Activity RelationshipThiazolesAnti-Infective AgentsAntiprotozoal AgentsNitrofuransPyrrolesThiazolesantimicrobial agentsdrug screening

Identifiers

PMID28396548
PMCPMC5444119
OpenAlexW2605700745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.