Evidence map›Paper›PMID 28396446›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Identification of a cono-RFamide from the venom of

Catharina Reimers, Cheng-Han Lee, Hubert Kalbacher, Yuemin Tian, Chih-Hsien Hung, Axel Schmidt, Lea Prokop, Silke Kauferstein, Dietrich Mebs, Chih-Cheng Chen and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Toxins in disguise: Neuropeptide mimicry across animal venoms.General and comparative endocrinology · 2026
    Review
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  18. Evolution of acid nociception: ion channels and receptors for detecting acid.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Catharina ReimersInstitute of Physiology, Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen University, 52074 Aachen, Germany.
Cheng-Han LeeInstitute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Hubert KalbacherInterfaculty Institute of Biochemistry, University of Tübingen, 72076 Tuebingen, Germany.
Yuemin TianInstitute of Physiology, Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen University, 52074 Aachen, Germany.
Chih-Hsien HungInstitute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Axel SchmidtInstitute of Physiology, Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen University, 52074 Aachen, Germany.
Lea ProkopDepartment of Immunology, Institute for Cell Biology, University of Tübingen, 72076 Tuebingen, Germany.
Silke KaufersteinInstitute of Legal Medicine, Goethe University of Frankfurt, 60596 Frankfurt, Germany.
Dietrich MebsInstitute of Legal Medicine, Goethe University of Frankfurt, 60596 Frankfurt, Germany.
Chih-Cheng ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Stefan GründerInstitute of Physiology, Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen University, 52074 Aachen, Germany; sgruender@ukaachen.de.ORCID 0000-0002-7635-9883
RWTH Aachen University · DEGoethe University Frankfurt · DEKaohsiung Medical University · TWUniversity of Tübingen · DEInstitute of Biomedical Sciences, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid-sensing ion channels (ASICs) are proton-gated Na

Indexed as

Acid Sensing Ion ChannelsAnimalsConotoxinsConus SnailGanglia, SpinalMiceMuscle, SkeletalMyalgiaNeuronsXenopus laevisAcid Sensing Ion ChannelsASIC3 protein, mouseConotoxinsConus textile toxinacid-sensing ion channelASICcone snailpainvenom

Identifiers

PMID28396446
PMCPMC5410773
OpenAlexW2606631328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.