ArticleNeuroImage2017
Chronic ambulatory electrocorticography from human speech cortex.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed.
- A guide to neuromodulation in drug-resistant epilepsy.Epileptic disorders : international epilepsy journal with videotape · 2026Review
- At-home movement state classification using totally implantable cortical-basal ganglia neural interface.Science advances · 2026Article
- Intracranial substrates of meditation-induced neuromodulation in the amygdala and hippocampus.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Decoding Single and Paired Phonemes Using 7T Functional MRI.Brain topography · 2024Article
- Online speech synthesis using a chronically implanted brain-computer interface in an individual with ALS.Scientific reports · 2024Article
- Timing and location of speech errors induced by direct cortical stimulation.Brain communications · 2024Article
- Stable Decoding from a Speech BCI Enables Control for an Individual with ALS without Recalibration for 3 Months.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Online speech synthesis using a chronically implanted brain-computer interface in an individual with ALS.medRxiv : the preprint server for health sciences · 2023Article
- Advances in human intracranial electroencephalography research, guidelines and good practices.NeuroImage · 2022Review
- Brain-Computer Interface: Applications to Speech Decoding and Synthesis to Augment Communication.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- The Efficacy, Safety, and Outcomes of Brain-responsive Neurostimulation (RNS® System) therapy in older adults.Epilepsia open · 2021Article
- Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria.The New England journal of medicine · 2021Article
- Effects of anterior thalamic nuclei stimulation on hippocampal activity: Chronic recording in a patient with drug-resistant focal epilepsy.Epilepsy & behavior reports · 2021Article
- Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans.Neuron · 2020Article
- Cortical and thalamic electrode implant followed by temporary continuous subthreshold stimulation yields long-term seizure freedom: A case report.Epilepsy & behavior reports · 2020Article
- Real-time decoding of question-and-answer speech dialogue using human cortical activity.Nature communications · 2019Article
- Hippocampal gamma predicts associative memory performance as measured by acute and chronic intracranial EEG.Scientific reports · 2019Article
- The Potential for a Speech Brain-Computer Interface Using Chronic Electrocorticography.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019Review
- Cognitive tasks and human ambulatory electrocorticography using the RNS System.Journal of neuroscience methods · 2019Article
- Running-down phenomenon captured with chronic electrocorticography.Epilepsia open · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Direct intracranial recording of human brain activity is an important approach for deciphering neural mechanisms of cognition. Such recordings, usually made in patients with epilepsy undergoing inpatient monitoring for seizure localization, are limited in duration and depend on patients' tolerance for the challenges associated with recovering from brain surgery. Thus, typical intracranial recordings, similar to most non-invasive approaches in humans, provide snapshots of brain activity in acute, highly constrained settings, limiting opportunities to understand long timescale and natural, real-world phenomena. A new device for treating some forms of drug-resistant epilepsy, the NeuroPace RNS® System, includes a cranially-implanted neurostimulator and intracranial electrodes that continuously monitor brain activity and respond to incipient seizures with electrical counterstimulation. The RNS System can record epileptic brain activity over years, but whether it can record meaningful, behavior-related physiological responses has not been demonstrated. Here, in a human subject with electrodes implanted over high-level speech-auditory cortex (Wernicke's area; posterior superior temporal gyrus), we report that cortical evoked responses to spoken sentences are robust, selective to phonetic features, and stable over nearly 1.5 years. In a second subject with RNS System electrodes implanted over frontal cortex (Broca's area, posterior inferior frontal gyrus), we found that word production during a naming task reliably evokes cortical responses preceding speech onset. The spatiotemporal resolution, high signal-to-noise, and wireless nature of this system's intracranial recordings make it a powerful new approach to investigate the neural correlates of human cognition over long timescales in natural ambulatory settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.