Co-trimoxazole for HIV-exposed uninfected infants.

Ceri Evans, Andrew J Prendergast

Abstract readComment

In one paragraph

Article in The Lancet. Global health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed, 2 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

Co-trimoxazole prophylaxis for children who are HIV-exposed and uninfected: a systematic review.Journal of the International AIDS Society · 2023
Pooled it
A Meta-analysis Assessing Diarrhea and Pneumonia in HIV-Exposed Uninfected Compared With HIV-Unexposed Uninfected Infants and Children.Journal of acquired immune deficiency syndromes (1999) · 2019
Pooled it
Quality assessment of selected co-trimoxazole suspension brands marketed in Nairobi County, Kenya.PloS one · 2021
Article
Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants.Scientific reports · 2019
Article
The prevalence and clinical characteristics of pertussis-associated pneumonia among infants in Botswana.BMC pediatrics · 2019
Article
Differential expression of Fas receptors (CD95) and Fas ligands (CD95L) in HIV infected and exposed uninfected children in Cameroon versus unexposed children.The Pan African medical journal · 2019
Article

4 · The record

Corrections and comments

Comment on
Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial.2017

5 · Who and what money

Authors and funding

2 authors.

Ceri EvansCentre for Genomics and Child Health, Blizard Institute, Queen Mary University of London, London E1 2AT, UK; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.

Andrew J PrendergastCentre for Genomics and Child Health, Blizard Institute, Queen Mary University of London, London E1 2AT, UK; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: a.prendergast@qmul.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIV InfectionsTrimethoprim, Sulfamethoxazole Drug CombinationHumansInfantTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID28395832

DOI10.1016/S2214-109X(17)30147-X

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.