Evidence map›Paper›PMID 28395105›Full record

ArticleAmerican journal of clinical pathology2017

T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting: 2015 SH/EAHP Workshop Report-Part 4.

Dita Gratzinger, Daphne de Jong, Elaine S Jaffe, Amy Chadburn, John K C Chan, John R Goodlad, Jonathan Said, Yasodha Natkunam

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Article in American journal of clinical pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Dita GratzingerFrom the Stanford University School of Medicine, Stanford, CA.
Daphne de JongVU University Medical Center, Amsterdam, the Netherlands.
Elaine S JaffeNational Institutes of Health, Bethesda, MD.
Amy ChadburnWeill Medical College of Cornell University, New York, NY.
John K C ChanQueen Elizabeth Hospital, Kowloon, Hong Kong.
John R GoodladUniversity of Leeds, Leeds, United Kingdom.
Jonathan SaidUniversity of California Los Angeles Medical Center, Los Angeles.
Yasodha NatkunamFrom the Stanford University School of Medicine, Stanford, CA.
Stanford University · USAmsterdam UMC Location VUmc · NLCornell University · USLos Angeles Medical Center · USNational Institutes of Health · USQueen Elizabeth Hospital · CNUniversity of Leeds · GB

Funding

Hematopathology DiagnosisZIABC011070 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$14.5M
6 · The paper itself

Abstract

objectivesThe 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology aimed to review immunodeficiency-related T- and natural killer (NK)-cell lymphoproliferations.

methodsThe Workshop Panel reviewed 88 T- or NK-cell lymphoproliferations and rendered consensus diagnoses.

resultsHyperplasias of T-cell subsets may be clonal; retained architecture and the clinical setting support a benign diagnosis. Specific associations include hepatosplenic T-cell lymphoma with iatrogenic immunosuppression and breast implants with an indolent variant of anaplastic large cell lymphoma. Epstein-Barr virus (EBV)-positive T-cell lymphomas rarely occur in the acquired immunodeficiency setting. Systemic T- and NK-cell lymphoma of childhood overlaps with chronic active EBV and reversible hemophagocytic lymphohistiocytosis-related T-cell lymphoproliferations.

conclusionsImmunodeficiencies predispose to T-cell hyperplasias, which must not be overdiagnosed as lymphoma. Many T-cell lymphomas in the immunodeficiency setting are likely coincidental, with specific exceptions. Systemic T- or NK-cell lymphomas are part of a spectrum of EBV+ T or NK lymphoproliferations and can present in the acquired immunodeficiency setting.

Indexed as

EducationEpstein-Barr Virus InfectionsFemaleHumansImmunologic Deficiency SyndromesLymphoma, Extranodal NK-T-CellLymphoma, T-CellLymphoproliferative DisordersMaleIatrogenic immunodeficiencyNK-cell lymphomaPosttransplant lymphoproliferative disorderSystemic T- or NK-cell lymphoma of childhoodT-cell lymphoma

Identifiers

PMID28395105
PMCPMC6248696
OpenAlexW2589291762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.