ArticleThe European journal of neuroscience2017
The retrosplenial cortex and object recency memory in the rat.
Article in The European journal of neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 52 citations in OpenAlex.
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- Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.Biological research · 2026Article
- Temporal differential effects of post-injury alcohol consumption in a mouse model of blast-induced traumatic brain injury.Neuroscience · 2024Article
- A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe.bioRxiv : the preprint server for biology · 2024Article
- Time Cells in the Retrosplenial Cortex.bioRxiv : the preprint server for biology · 2024Article
- A distributed and efficient population code of mixed selectivity neurons for flexible navigation decisions.Nature communications · 2023Article
- Review
- Altered pattern separation in Goto-Kakizaki rats.Current research in neurobiology · 2023Article
- Neuronal circuitry for recognition memory of object and place in rodent models.Neuroscience and biobehavioral reviews · 2022Review
- Unique roles for the anterior and posterior retrosplenial cortices in encoding and retrieval of memory for context.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Article
- Aberrant miR-339-5p/neuronatin signaling causes prodromal neuronal calcium dyshomeostasis in mutant presenilin mice.The Journal of clinical investigation · 2022Article
- The gut-microbiota-brain changes across the liver disease spectrum.Frontiers in cellular neuroscience · 2022Article
- A Positively Selected MAGEE2 LoF Allele Is Associated with Sexual Dimorphism in Human Brain Size and Shows Similar Phenotypes in Magee2 Null Mice.Molecular biology and evolution · 2021Article
- Retrosplenial cortex in spatial memory: focus on immediate early genes mapping.Molecular brain · 2021Review
- The anterior thalamic nuclei and cognition: A role beyond space?Neuroscience and biobehavioral reviews · 2021Review
- Time to put the mammillothalamic pathway into context.Neuroscience and biobehavioral reviews · 2021Review
- Episodic-like memory of rats as retrospective retrieval of incidentally encoded locations and involvement of the retrosplenial cortex.Scientific reports · 2021Article
- The protective effect of early dietary fat consumption on Alzheimer's disease-related pathology and cognitive function in mice.Alzheimer's & dementia (New York, N. Y.) · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
It has been proposed that the retrosplenial cortex forms part of a 'where/when' information network. The present study focussed on the related issue of whether retrosplenial cortex also contributes to 'what/when' information, by examining object recency memory. In Experiment 1, rats with retrosplenial lesions were found to be impaired at distinguishing the temporal order of objects presented in a continuous series ('Within-Block' condition). The same lesioned rats could, however, distinguish between objects that had been previously presented in one of two discrete blocks ('Between-Block' condition). Experiment 2 used intact rats to map the expression of the immediate-early gene c-fos in retrosplenial cortex following performance of a between-block, recency discrimination. Recency performance correlated positively with levels of c-fos expression in both granular and dysgranular retrosplenial cortex (areas 29 and 30). Expression of c-fos in the granular retrosplenial cortex also correlated with prelimbic cortex and ventral subiculum c-fos activity, the latter also correlating with recency memory performance. The combined findings from both experiments reveal an involvement of the retrosplenial cortex in temporal order memory, which includes both between-block and within-block problems. The current findings also suggest that the rat retrosplenial cortex comprises one of a group of closely interlinked regions that enable recency memory, including the hippocampal formation, medial diencephalon and medial frontal cortex. In view of the well-established importance of the retrosplenial cortex for spatial learning, the findings support the notion that, with its frontal and hippocampal connections, retrosplenial cortex has a key role for both what/when and where/when information.
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