Evidence map›Paper›PMID 28394324›Full record

ArticleNature neuroscience2017

Abnormal wiring of CCK

Isabel Del Pino, Jorge R Brotons-Mas, André Marques-Smith, Aline Marighetto, Andreas Frick, Oscar Marín, Beatriz Rico

Open access · greenAbstract read
In one paragraph

Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
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  3. NPAS4 refines spatial and temporal firing in CA1 pyramidal neurons.bioRxiv : the preprint server for biology · 2026
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  15. Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025
    Review
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  19. A Novel Needle Mouse Model of Vascular Cognitive Impairment and Dementia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Isabel Del Pino *Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, United Kingdom.
Jorge R Brotons-Mas *Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas & Universidad Miguel Hernández, Sant Joan d'Alacant 03550, Spain.
André Marques-SmithCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, United Kingdom.
Aline MarighettoNeurocentre Magendie INSERM U1215, 33077 Bordeaux, France.
Andreas FrickNeurocentre Magendie INSERM U1215, 33077 Bordeaux, France.
Oscar MarínCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, United Kingdom.
Beatriz RicoCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, United Kingdom.
Consejo Superior de Investigaciones Científicas · ESInserm · FRKing's College London · GB

Funding

European Research Council 293683Medical Research Council MR/N026063/1Wellcome Trust
6 · The paper itself

Abstract

The function of cortical GABAergic interneurons is largely determined by their integration into specific neural circuits, but the mechanisms controlling the wiring of these cells remain largely unknown. This is particularly true for a major population of basket cells that express the neuropeptide cholecystokinin (CCK). Here we found that the tyrosine kinase receptor ErbB4 was required for the normal integration into cortical circuits of basket cells expressing CCK and vesicular glutamate transporter 3 (VGlut3). The number of inhibitory synapses made by CCK

Indexed as

Amino Acid Transport Systems, AcidicAnimalsCA1 Region, HippocampalCerebral CortexCholecystokininExploratory BehaviorGABAergic NeuronsInterneuronsLocomotionMaleMaze LearningMiceMice, TransgenicNeural InhibitionNeural PathwaysPlace CellsAmino Acid Transport Systems, AcidicCholecystokininReceptor, ErbB-4Slc17a8 protein, mouse

Identifiers

PMID28394324
PMCPMC5446788
OpenAlexW2606468927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.