Evidence map›Paper›PMID 28394296›Full record

ArticleSensors (Basel, Switzerland)2017

Comparison between a Direct-Flow SPR Immunosensor for Ampicillin and a Competitive Conventional Amperometric Device: Analytical Features and Possible Applications to Real Samples.

Mauro Tomassetti, Giovanni Merola, Elisabetta Martini, Luigi Campanella, Gabriella Sanzò, Gabriele Favero, Franco Mazzei

Abstract readComparative Study
In one paragraph

Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mauro TomassettiDepartment of Chemistry, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. mauro.tomassetti@uniroma1.it.
Giovanni MerolaDepartment of Chemistry, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. gancetto2@hotmail.it.
Elisabetta MartiniDepartment of Chemistry, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. elisabettamartini@libero.it.
Luigi CampanellaDepartment of Chemistry, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. luigi.campanella@uniroma1.it.
Gabriella SanzòDepartment of Chemistry and Pharmacy Technology, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. gabriella.sanzo@uniroma1.it.
Gabriele FaveroDepartment of Chemistry and Pharmacy Technology, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. gabriele.favero@uniroma1.it.
Franco MazzeiDepartment of Chemistry and Pharmacy Technology, "Sapienza" University of Rome, P.le A. Moro, 5, 00185 Rome, Italy. franco.mazzei@uniroma1.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, we developed a direct-flow surface plasmon resonance (SPR) immunosensor for ampicillin to perform direct, simple, and fast measurements of this important antibiotic. In order to better evaluate the performance, it was compared with a conventional amperometric immunosensor, working with a competitive format with the aim of finding out experimental real advantages and disadvantages of two respective methods. Results showed that certain analytical features of the new SPR immunodevice, such as the lower limit of detection (LOD) value and the width of the linear range, are poorer than those of a conventional amperometric immunosensor, which adversely affects the application to samples such as natural waters. On the other hand, the SPR immunosensor was more selective to ampicillin, and measurements were more easily and quickly attained compared to those performed with the conventional competitive immunosensor.

Indexed as

Surface Plasmon ResonanceAmpicillinAnti-Bacterial AgentsBiosensing TechniquesImmunoassayAmpicillinAnti-Bacterial Agentsampicillinanalytical comparisoncompetitive amperometric immunosensorflow surface plasmon resonance (SPR) immunosensor

Identifiers

PMID28394296
PMCPMC5422180

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.