Evidence map›Paper›PMID 28394276›Full record

ArticleNutrients2017

Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.

Lucília P Pereira, Patrícia Silva, Marlene Duarte, Liliana Rodrigues, Catarina M M Duarte, Cristina Albuquerque, Ana Teresa Serra

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Quantitative Determination of 15 Active Components inJournal of analytical methods in chemistry · 2021
    Article
  12. Article
  13. Article
  14. Rapha MyrInternational journal of molecular sciences · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Controlling metastatic cancer: the role of phytochemicals in cell signaling.Journal of cancer research and clinical oncology · 2019
    Review
  19. Osteopontin Promotes Colorectal Cancer Cell Invasion and the Stem Cell-Like Properties through the PI3K-AKT-GSK/3β-β/Catenin Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lucília P PereiraiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal. lu.pebre.pereira@gmail.com.
Patrícia SilvaUnidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E (IPOLFG, EPE), 1099-023 Lisboa, Portugal. palsilva@ipolisboa.min-saude.pt.
Marlene DuarteUnidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E (IPOLFG, EPE), 1099-023 Lisboa, Portugal. mrcduarte@ipolisboa.min-saude.pt.
Liliana RodriguesiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal. liliana.rodrigues@ibet.pt.
Catarina M M DuarteiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal. cduarte@itqb.unl.pt.
Cristina AlbuquerqueUnidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E (IPOLFG, EPE), 1099-023 Lisboa, Portugal. mc.albuquerque@sapo.pt.
Ana Teresa SerraiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal. tserra@ibet.pt.
Universidade Nova de Lisboa · PTInstituto de Biologia Experimental e Tecnológica · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) recurrence is often attributable to circulating tumor cells and/or cancer stem cells (CSCs) that resist to conventional therapies and foster tumor progression. Isothiocyanates (ITCs) derived from

Indexed as

Anticarcinogenic AgentsAntineoplastic Agents, PhytogenicBiomarkers, TumorBrassicaCaco-2 CellsCarbon DioxideCell DifferentiationCell ProliferationColorectal NeoplasmsDietary SupplementsDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHT29 CellsHumansIsothiocyanatesNasturtiumAnticarcinogenic AgentsAntineoplastic Agents, PhytogenicBiomarkers, TumorCarbon DioxideIsothiocyanatesphenethyl isothiocyanatePlant ExtractsSolventssulforaphaneSulfoxidesBrassicaceae extractsbroccolicancer stem cellscolorectal cancermetastasisphenethyl isothiocyanatesulforaphanewatercress

Identifiers

PMID28394276
PMCPMC5409707
OpenAlexW2606952730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.