Evidence map›Paper›PMID 28393895›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017

Sex Differences in Regional Brain Glucose Metabolism Following Opioid Withdrawal and Replacement.

Giovanni C Santoro, Joseph Carrion, Krishna Patel, Crystal Vilchez, Jennifer Veith, Jonathan D Brodie, Stephen L Dewey

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Giovanni C SantoroCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Joseph CarrionCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Krishna PatelCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Crystal VilchezCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Jennifer VeithCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Jonathan D BrodiePsychiatry Department, New York University School of Medicine, New York, NY, USA.
Stephen L DeweyCenter for Neurosciences, Laboratory for Molecular and Behavioral Neuroimaging, Feinstein Institute for Medical Research, Manhasset, NY, USA.
Feinstein Institute for Medical Research · USCenter for Neurosciences · USHofstra University · USNew York University · US

Funding

Treating Adolsecent and Adult Methamphetamine or Inhalant Abuse with S-(+)-GVGK02DA022346 · NIDA · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DEWEY, STEPHEN L · 2007 to 2011
$671k
NIDA NIH HHS K02 DA022346
6 · The paper itself

Abstract

Methadone and buprenorphine are currently the most common pharmacological treatments for opioid dependence. Interestingly, the clinical response to these drugs appears to be sex specific. That is, females exhibit superior therapeutic efficacy, defined as extended periods of abstinence and longer time to relapse, compared with males. However, the underlying metabolic effects of opioid withdrawal and replacement have not been examined. Therefore, using

Indexed as

Sex CharacteristicsAnalgesics, OpioidAnimalsBrainBrain MappingBuprenorphineCross-Sectional StudiesDisease Models, AnimalFemaleFluorodeoxyglucose F18GlucoseLongitudinal StudiesMaleMethadoneMorphineMorphine DependenceAnalgesics, OpioidBuprenorphineFluorodeoxyglucose F18GlucoseMethadoneMorphineRadiopharmaceuticals

Identifiers

PMID28393895
PMCPMC5520789
OpenAlexW2607065815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.