ArticleNature communications2017
Oxidative 1,2-carboamination of alkenes with alkyl nitriles and amines toward γ-amino alkyl nitriles.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cu-Catalyzed Three-Component Alkene Carboamination: Mechanistic Insights and Rational Design to Overcome Limitations.Journal of the American Chemical Society · 2024Article
- Photoexcitation of (diarylmethylene)amino benziodoxolones for alkylamination of styrene derivatives with carboxylic acids.Chemical science · 2024Article
- Cu-Catalyzed Three-Component Carboamination of Electron Deficient Olefins.Organic letters · 2023Article
- Metal-free photosensitized radical relay 1,4-carboimination across two distinct olefins.Chemical science · 2023Article
- Metal-Free Photochemical Imino-Alkylation of Alkenes with Bifunctional Oxime Esters.Journal of the American Chemical Society · 2022Article
- Three-component 1,2-carboamination of vinyl boronic estersChemical science · 2021Article
- Oxidative Three-Component Carboamination of Vinylarenes with Alkylboronic Acids.ACS catalysis · 2021Article
- Iron-catalyzed domino coupling reactions of π-systems.Beilstein journal of organic chemistry · 2021Review
- Synthesis of Benzylureas and Related Amine Derivatives via Copper-Catalyzed Three-Component Carboamination of Styrenes.Organic letters · 2020Article
- Copper-Catalyzed 1,2-Aminocyanation of Unactivated Alkenes via Cyano Migration.Organic letters · 2020Article
- Cyanomethylation of Substituted Fluorenes and Oxindoles with Alkyl Nitriles.Organic letters · 2020Article
- Photosensitized Intermolecular Carboimination of Alkenes through the Persistent Radical Effect.Angewandte Chemie (International ed. in English) · 2020Article
- Carboamination of Unactivated Alkenes through Three-Component Radical Conjugate Addition.Angewandte Chemie (International ed. in English) · 2019Article
- Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents.Nature communications · 2019Article
- Article
- Copper-catalyzed methylative difunctionalization of alkenes.Nature communications · 2018Article
- Heck Reaction of Electronically Diverse Tertiary Alkyl Halides.Organic letters · 2018Article
- Cu-Catalyzed Three-Component Carboamination of Alkenes.Journal of the American Chemical Society · 2018Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Difunctionalization of alkenes has become a powerful tool for quickly increasing molecular complexity in synthesis. Despite significant progress in the area of alkene difunctionalization involving the incorporation of a nitrogen atom across the C-C double bonds, approaches for the direct 1,2-carboamination of alkenes to produce linear N-containing molecules are scarce and remain a formidable challenge. Here we describe a radical-mediated oxidative intermolecular 1,2-alkylamination of alkenes with alkyl nitriles and amines involving C(sp
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