ReviewCurrent medicinal chemistry2018
Metallic Nanoclusters for Cancer Imaging and Therapy.
Review in Current medicinal chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Nano-Metal Hydrogen Therapy Targeting Immune Cells Drives Synergistic Anti-Tumor Effects.Molecules (Basel, Switzerland) · 2026Review
- PEG/Folic Acid Coloaded Er:YACS omega · 2026Article
- Daunomycin Nanocarriers with High Therapeutic Payload for the Treatment of Childhood Leukemia.Pharmaceutics · 2025Article
- DFT studies of metal oxide nanocluster as a possible drug delivery system for mechlorethamine.BMC chemistry · 2025Article
- Studies upon Fluorescent Modulation of Silver Nanoclusters Formed on Bifunctional DNA Template.International journal of molecular sciences · 2025Article
- A practical post-Hartree-Fock approach describing open-shell metal cluster-support interactions. Application to CuRSC advances · 2024Article
- Effect of different crystal forms of MnOMikrochimica acta · 2024Article
- Theranostic and Combined Approaches Exploiting Multifunctional Gold Nanoclusters in Tumoral Ecosystems: A Paradigm Shift in Precision Oncology.Current radiopharmaceuticals · 2024Review
- Application of Gold Nanoparticles as Radiosensitizer for Metastatic Prostate Cancer Cell Lines.International journal of molecular sciences · 2023Article
- Gold Nanoclusters as Nanoantibiotic Auranofin Analogues.Advanced healthcare materials · 2022Article
- Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis.Nanomaterials (Basel, Switzerland) · 2022Review
- Review
- Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications.Bioconjugate chemistry · 2022Review
- Green Synthesis of Gold Nanoparticles Using Plant Extracts as Beneficial Prospect for Cancer Theranostics.Molecules (Basel, Switzerland) · 2021Review
- Biomarker sensing platforms based on fluorescent metal nanoclusters.Nanoscale advances · 2021Review
- Gold Nanoparticles in Cancer Theranostics.Frontiers in bioengineering and biotechnology · 2021Review
- Gold Nanoparticles: A New Golden Era in Oncology?Pharmaceuticals (Basel, Switzerland) · 2020Review
- Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences.Scientific reports · 2020Article
- Ultra-Small Lysozyme-Protected Gold Nanoclusters as Nanomedicines Inducing Osteogenic Differentiation.International journal of nanomedicine · 2020Article
- Gold Nanoparticles in Diagnostics and Therapeutics for Human Cancer.International journal of molecular sciences · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundNanoclusters are made of a few to tens of atoms with a size below 2 nm. Compared with nanoparticles, they exhibited excellent properties, such as tunable fluorescence, ease of conjugation, high quantum yield and biocompatibility, which are highly desired in the development of cancer nanotheranostics. Hence, the metallic nanoclusters have emerged as a newcomer in cancer nanomedicines. This review aims to summarize recently developed approaches to preparing metallic nanoclusters, highlight their applications in cancer theranostics, and provide a brief outlook for the future developments of nanoclusters in nanomedicine.
methodWe carried out a thorough literature search using online databases. The search was focused on a centered question. Irrelevant articles were excluded after further examination and directly relevant articles were included. The relevant articles were classified by the subjects and the information from these articles was synthesized.
resultsOne hundred and forty-three articles were included in this review. About eighty articles outlined the development in the synthetic methods of nanoclusters. The synthesis approaches include chemical reduction, photoreduction and so on. The progress in the application of gold and silver nanoclusters to cancer theranostics was described in fifteen and eight articles, respectively. The rest articles were about the advancements in the use of other metal nanoclusters and nanocluster nanocomposites as cancer theranostic agents.
conclusionThis review summarizes the synthesis and use of metallic nanoclusters or their nanocomposites as cancer theranostic agents. It confirms their importance, advantages and potentials in serving as a new generation of cancer theranostics in clinics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.